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Volume 462

Insights into substrate binding and catalysis in bacterial type I dehydroquinase
Published as BJ Immediate Publication 24 June 2014, doi:10.1042/BJ20140614
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Elucidation of the preferred routes of C8-vinyl reduction in chlorophyll and bacteriochlorophyll biosynthesis
Published as BJ Immediate Publication 19 June 2014, doi:10.1042/BJ20140163
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Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme
Published as BJ Immediate Publication 20 June 2014, doi:10.1042/BJ20140382
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The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine–glyoxylate aminotransferase
Published as BJ Immediate Publication 24 June 2014, doi:10.1042/BJ20140250
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Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones
Published as BJ Immediate Publication 20 June 2014, doi:10.1042/BJ20131640
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Crystal structures and functional studies clarify substrate selectivity and catalytic residues for the unique orphan enzyme N-acetyl-D-mannosamine dehydrogenase
Published as BJ Immediate Publication 27 June 2014, doi:10.1042/BJ20140266
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Amyloid β-peptide-dependent activation of human platelets: essential role for Ca2+ and ADP in aggregation and thrombus formation
Published as BJ Immediate Publication 1 July 2014, doi:10.1042/BJ20140307
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Incorporating covalent and allosteric effects into rate equations: the case of muscle glycogen synthase
Published as BJ Immediate Publication 27 June 2014, doi:10.1042/BJ20140196
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Molecular evolution of the substrate specificity of ent-kaurene synthases to adapt to gibberellin biosynthesis in land plants
Published as BJ Immediate Publication 1 July 2014, doi:10.1042/BJ20140134
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Selenoprotein S is involved in maintenance and transport of multiprotein complexes
Published as BJ Immediate Publication 4 June 2014, doi:10.1042/BJ20140076
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Regulation of PKA activity by an autophosphorylation mechanism in Saccharomyces cerevisiae
Published as BJ Immediate Publication 20 June 2014, doi:10.1042/BJ20140577
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Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile
Published as BJ Immediate Publication 19 June 2014, doi:10.1042/BJ20140511
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Complete pyridine-nucleotide-specific conversion of an NADH-dependent ferredoxin reductase
Published as BJ Immediate Publication 6 June 2014, doi:10.1042/BJ20140384
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Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila
Published as BJ Immediate Publication 24 June 2014, doi:10.1042/BJ20130923
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Potent inhibition of macrophage migration inhibitory factor (MIF) by myeloperoxidase-dependent oxidation of epicatechins
Published as BJ Immediate Publication 11 June 2014, doi:10.1042/BJ20140612
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HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens
Published as BJ Immediate Publication 20 May 2014, doi:10.1042/BJ20140174
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Recombinant form of mammalian gp91phox is active in the absence of p22phox
Published as BJ Immediate Publication 3 June 2014, doi:10.1042/BJ20131620
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Key elements of the RNAi pathway are regulated by hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing
Published as BJ Immediate Publication 6 June 2014, doi:10.1042/BJ20140316
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Archaeal MBF1 binds to 30S and 70S ribosomes via its helix–turn–helix domain
Published as BJ Immediate Publication 14 May 2014, doi:10.1042/BJ20131474
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Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants
Published as BJ Immediate Publication 14 May 2014, doi:10.1042/BJ20140390
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Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain
Published as BJ Immediate Publication 20 May 2014, doi:10.1042/BJ20140521
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Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice
Published as BJ Immediate Publication 20 May 2014, doi:10.1042/BJ20140423
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TM4SF5 suppression disturbs integrin α5-related signalling and muscle development in zebrafish
Published as BJ Immediate Publication 4 June 2014, doi:10.1042/BJ20140177
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miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia
Published as BJ Immediate Publication 4 June 2014, doi:10.1042/BJ20140486
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Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1
Published as BJ Immediate Publication 10 June 2014, doi:10.1042/BJ20140425
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N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation
Published as BJ Immediate Publication 29 May 2014, doi:10.1042/BJ20140494
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The author has paid for access to this article to be freely available Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis
Published as BJ Immediate Publication 16 May 2014, doi:10.1042/BJ20131422
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Rate of steroid double-bond reduction catalysed by the human steroid 5β-reductase (AKR1D1) is sensitive to steroid structure: implications for steroid metabolism and bile acid synthesis
Published as BJ Immediate Publication 4 June 2014, doi:10.1042/BJ20140220
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Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio
Published as BJ Immediate Publication 28 May 2014, doi:10.1042/BJ20130992
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Reversible disassembly of the yeast V-ATPase revisited under in vivo conditions
Published as BJ Immediate Publication 7 May 2014, doi:10.1042/BJ20131293
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Volume 461

The author has paid for access to this article to be freely available An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
Published as BJ Immediate Publication 9 June 2014, doi:10.1042/BJ20140444
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PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
Published as BJ Immediate Publication 19 May 2014, doi:10.1042/BJ20140132
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Hypoxia-inducible regulation of placental BOK expression
Published as BJ Immediate Publication 8 May 2014, doi:10.1042/BJ20140066
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Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2
Published as BJ Immediate Publication 12 May 2014, doi:10.1042/BJ20131618
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Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies
Published as BJ Immediate Publication 1 May 2014, doi:10.1042/BJ20140219
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Effect of the guide strand 3′-end structure on the gene-silencing potency of asymmetric siRNA
Published as BJ Immediate Publication 6 May 2014, doi:10.1042/BJ20140407
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Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization
Published as BJ Immediate Publication 22 May 2014, doi:10.1042/BJ20130709
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Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats
Published as BJ Immediate Publication 19 May 2014, doi:10.1042/BJ20131208
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TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition
Published as BJ Immediate Publication 16 May 2014, doi:10.1042/BJ20140337
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Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure–activity relationships and mode of action
Published as BJ Immediate Publication 12 May 2014, doi:10.1042/BJ20131524
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PKG and NHR-49 signalling co-ordinately regulate short-term fasting-induced lysosomal lipid accumulation in C. elegans
Published as BJ Immediate Publication 23 May 2014, doi:10.1042/BJ20140191
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c-Fos-activated synthesis of nuclear phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] promotes global transcriptional changes
Published as BJ Immediate Publication 13 May 2014, doi:10.1042/BJ20131376
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Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20140051
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The author has paid for access to this article to be freely available Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site
Published as BJ Immediate Publication 25 April 2014, doi:10.1042/BJ20140189
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Mitochondrial–nuclear genome interactions in non-alcoholic fatty liver disease in mice
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20131433
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Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase
Published as BJ Immediate Publication 2 May 2014, doi:10.1042/BJ20140408
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Conserved residues that modulate protein trans-splicing of Npu DnaE split intein
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20140287
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The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications
Published as BJ Immediate Publication 24 April 2014, doi:10.1042/BJ20131240
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Detergent-free purification of ABC (ATP-binding-cassette) transporters
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20131477
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Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise
Published as BJ Immediate Publication 30 April 2014, doi:10.1042/BJ20131456
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Prediction of high- and low-affinity quinol-analogue-binding sites in the aa3 and bo3 terminal oxidases from Bacillus subtilis and Escherichia coli1
Published as BJ Immediate Publication 30 April 2014, doi:10.1042/BJ20140082
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Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques
Published as BJ Immediate Publication 2 May 2014, doi:10.1042/BJ20140374
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The glycation site specificity of human serum transferrin is a determinant for transferrin's functional impairment under elevated glycaemic conditions
Published as BJ Immediate Publication 10 April 2014, doi:10.1042/BJ20140133
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Genome-wide profiling reveals a role for T-cell intracellular antigens TIA1 and TIAR in the control of translational specificity in HeLa cells
Published on the Internet 13 June 2014, doi:10.1042/BJ20140227
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Roundabout 1 exists predominantly as a basal dimeric complex and this is unaffected by binding of the ligand Slit2
Published as BJ Immediate Publication 27 March 2014, doi:10.1042/BJ20140190
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Soya bean Gα proteins with distinct biochemical properties exhibit differential ability to complement Saccharomyces cerevisiae gpa1 mutant
Published as BJ Immediate Publication 2 April 2014, doi:10.1042/BJ20131341
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Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis
Published as BJ Immediate Publication 9 April 2014, doi:10.1042/BJ20140209
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The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20140126
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The author has paid for access to this article to be freely available Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52
Published as BJ Immediate Publication 22 April 2014, doi:10.1042/BJ20140232
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Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice
Published as BJ Immediate Publication 16 April 2014, doi:10.1042/BJ20130915
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Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo
Published as BJ Immediate Publication 23 April 2014, doi:10.1042/BJ20131438
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Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia
Published as BJ Immediate Publication 17 April 2014, doi:10.1042/BJ20131242
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Volume 460

Non-preferential fuelling of the Na+/K+-ATPase pump
Published as BJ Immediate Publication 25 March 2014, doi:10.1042/BJ20140003
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A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators
Published as BJ Immediate Publication 25 March 2014, doi:10.1042/BJ20131673
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Histone chaperone Chz1 facilitates the disfavouring property of Spt16 to H2A.Z-containing genes in Saccharomyces cerevisiae
Published as BJ Immediate Publication 8 April 2014, doi:10.1042/BJ20140186
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T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses
Published as BJ Immediate Publication 25 March 2014, doi:10.1042/BJ20140040
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Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells
Published as BJ Immediate Publication 28 March 2014, doi:10.1042/BJ20131361
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A Fab fragment directed against the neural cell adhesion molecule L1 enhances functional recovery after injury of the adult mouse spinal cord
Published as BJ Immediate Publication 27 March 2014, doi:10.1042/BJ20131677
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C/EBPβ (CCAAT/enhancer-binding protein β) mediates progesterone production through transcriptional regulation in co-operation with SF-1 (steroidogenic factor-1)
Published as BJ Immediate Publication 18 March 2014, doi:10.1042/BJ20131522
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Casein kinase: the triple meaning of a misnomer
Published on the Internet 13 May 2014, doi:10.1042/BJ20140178
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The author has paid for access to this article to be freely available Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction
Published as BJ Immediate Publication 21 March 2014, doi:10.1042/BJ20131639
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The author has paid for access to this article to be freely available Trafficking modulator TENin1 inhibits endocytosis, causes endomembrane protein accumulation at the pre-vacuolar compartment and impairs gravitropic response in Arabidopsis thaliana
Published as BJ Immediate Publication 21 March 2014, doi:10.1042/BJ20131136
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The author has paid for access to this article to be freely available Mitochondrial thiol oxidase Erv1: both shuttle cysteine residues are required for its function with distinct roles
Published as BJ Immediate Publication 13 March 2014, doi:10.1042/BJ20131540
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Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors
Published as BJ Immediate Publication 4 March 2014, doi:10.1042/BJ20131139
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Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans
Published as BJ Immediate Publication 13 March 2014, doi:10.1042/BJ20140010
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The author has paid for access to this article to be freely available Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation
Published as BJ Immediate Publication 18 March 2014, doi:10.1042/BJ20140153
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Human P450-like oxidation of diverse proton pump inhibitor drugs by ‘gatekeeper’ mutants of flavocytochrome P450 BM3
Published as BJ Immediate Publication 4 March 2014, doi:10.1042/BJ20140030
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The author has paid for access to this article to be freely available Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor
Published as BJ Immediate Publication 18 March 2014, doi:10.1042/BJ20131553
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Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB
Published as BJ Immediate Publication 19 March 2014, doi:10.1042/BJ20131648
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The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization
Published as BJ Immediate Publication 14 March 2014, doi:10.1042/BJ20130945
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Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock
Published as BJ Immediate Publication 10 March 2014, doi:10.1042/BJ20131666
Abstract | Full text HTML | Full text PDF | Online Data
Casein kinase: the triple meaning of a misnomer
Published on the Internet 13 May 2014, doi:10.1042/BJ20140178
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction
Published as BJ Immediate Publication 21 March 2014, doi:10.1042/BJ20131639
Abstract | Full text HTML | Full text PDF | Online Data
Trafficking modulator TENin1 inhibits endocytosis, causes endomembrane protein accumulation at the pre-vacuolar compartment and impairs gravitropic response in Arabidopsis thaliana
Published as BJ Immediate Publication 21 March 2014, doi:10.1042/BJ20131136
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Mitochondrial thiol oxidase Erv1: both shuttle cysteine residues are required for its function with distinct roles
Published as BJ Immediate Publication 13 March 2014, doi:10.1042/BJ20131540
Abstract | Full text HTML | Full text PDF | Online Data
Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors
Published as BJ Immediate Publication 4 March 2014, doi:10.1042/BJ20131139
Abstract | Full text HTML | Full text PDF | Online Data
Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans
Published as BJ Immediate Publication 13 March 2014, doi:10.1042/BJ20140010
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation
Published as BJ Immediate Publication 18 March 2014, doi:10.1042/BJ20140153
Abstract | Full text HTML | Full text PDF | Online Data
Human P450-like oxidation of diverse proton pump inhibitor drugs by ‘gatekeeper’ mutants of flavocytochrome P450 BM3
Published as BJ Immediate Publication 4 March 2014, doi:10.1042/BJ20140030
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor
Published as BJ Immediate Publication 18 March 2014, doi:10.1042/BJ20131553
Abstract | Full text HTML | Full text PDF | Online Data
Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB
Published as BJ Immediate Publication 19 March 2014, doi:10.1042/BJ20131648
Abstract | Full text HTML | Full text PDF | Online Data
The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization
Published as BJ Immediate Publication 14 March 2014, doi:10.1042/BJ20130945
Abstract | Full text HTML | Full text PDF | Online Data
Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock
Published as BJ Immediate Publication 10 March 2014, doi:10.1042/BJ20131666
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
Published as BJ Immediate Publication 25 March 2014, doi:10.1042/BJ20140334
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In vitro characterization of bacterial and chloroplast Hsp70 systems reveals an evolutionary optimization of the co-chaperones for their Hsp70 partner
Published as BJ Immediate Publication 25 February 2014, doi:10.1042/BJ20140001
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The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway
Published on the Internet 25 April 2014, doi:10.1042/BJ20131467
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Occurrence and subcellular distribution of the NAD(P)HX repair system in mammals
Published as BJ Immediate Publication 10 March 2014, doi:10.1042/BJ20131482
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Functional divergence between the two P1–P2 stalk dimers on the ribosome in their interaction with ricin A chain
Published as BJ Immediate Publication 28 February 2014, doi:10.1042/BJ20140014
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Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells
Published as BJ Immediate Publication 4 March 2014, doi:10.1042/BJ20131424
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Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins
Published as BJ Immediate Publication 13 March 2014, doi:10.1042/BJ20140107
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The author has paid for access to this article to be freely available Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerization
Published as BJ Immediate Publication 20 February 2014, doi:10.1042/BJ20131650
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miR-30b regulates migration and invasion of human colorectal cancer via SIX1
Published as BJ Immediate Publication 5 March 2014, doi:10.1042/BJ20131535
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Volume 459

A novel p38 MAPK docking-groove-targeted compound is a potent inhibitor of inflammatory hyperalgesia
Published as BJ Immediate Publication 11 February 2014, doi:10.1042/BJ20130172
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Ser119 phosphorylation modulates the activity and conformation of PRRXL1, a homeodomain transcription factor
Published as BJ Immediate Publication 24 February 2014, doi:10.1042/BJ20131014
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Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival
Published as BJ Immediate Publication 20 February 2014, doi:10.1042/BJ20130903
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The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron–sulfur cluster biogenesis and oxidative stress defence
Published as BJ Immediate Publication 19 February 2014, doi:10.1042/BJ20130732
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Chitinase-3-like protein 1 protects skeletal muscle from TNFα-induced inflammation and insulin resistance
Published as BJ Immediate Publication 11 February 2014, doi:10.1042/BJ20131151
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Suppression of adipogenesis by valproic acid through repression of USF1-activated fatty acid synthesis in adipocytes
Published as BJ Immediate Publication 11 February 2014, doi:10.1042/BJ20131476
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Inhibition of histone binding by supramolecular hosts
Published as BJ Immediate Publication 28 February 2014, doi:10.1042/BJ20140145
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The increase in BIK expression following ERK1/2 pathway inhibition is a consequence of G1 cell-cycle arrest and not a direct effect on BIK protein stability
Published as BJ Immediate Publication 17 February 2014, doi:10.1042/BJ20131346
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Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in Streptomyces lividans
Published as BJ Immediate Publication 19 February 2014, doi:10.1042/BJ20140017
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The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s)
Published as BJ Immediate Publication 21 February 2014, doi:10.1042/BJ20131681
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Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence
Published as BJ Immediate Publication 26 February 2014, doi:10.1042/BJ20131363
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Assembly of the TgrB1–TgrC1 cell adhesion complex during Dictyostelium discoideum development
Published as BJ Immediate Publication 3 February 2014, doi:10.1042/BJ20131594
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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
Published as BJ Immediate Publication 27 January 2014, doi:10.1042/BJ20131344
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Plant cyclopropylsterol-cycloisomerase: key amino acids affecting activity and substrate specificity
Published as BJ Immediate Publication 3 February 2014, doi:10.1042/BJ20131239
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Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Published as BJ Immediate Publication 12 February 2014, doi:10.1042/BJ20131471
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The author has paid for access to this article to be freely available The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation
Published as BJ Immediate Publication 7 February 2014, doi:10.1042/BJ20140073
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Identification of interferon-γ as a new molecular target of liver X receptor
Published as BJ Immediate Publication 20 January 2014, doi:10.1042/BJ20131442
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Differential functions of calpain 1 during epithelial cell death and adipocyte differentiation in mammary gland involution
Published as BJ Immediate Publication 27 January 2014, doi:10.1042/BJ20130847
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Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site
Published as BJ Immediate Publication 5 February 2014, doi:10.1042/BJ20131664
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The author has paid for access to this article to be freely available Bacillus thuringiensis Cry1A toxins are versatile proteins with multiple modes of action: two distinct pre-pores are involved in toxicity
Published as BJ Immediate Publication 23 January 2014, doi:10.1042/BJ20131408
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Bax channel triplet: co-operativity and voltage gating
Published as BJ Immediate Publication 6 February 2014, doi:10.1042/BJ20131441
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GLCE regulates PC12 cell neuritogenesis induced by nerve growth factor through activating SMAD/ID3 signalling
Published as BJ Immediate Publication 5 February 2014, doi:10.1042/BJ20131360
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S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment
Published as BJ Immediate Publication 29 January 2014, doi:10.1042/BJ20131037
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Multisite phosphorylation of 14-3-3 proteins by calcium-dependent protein kinases
Published as BJ Immediate Publication 3 January 2014, doi:10.1042/BJ20130035
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Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization
Published as BJ Immediate Publication 3 January 2014, doi:10.1042/BJ20131067
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Substrate interaction dynamics and oxygen control in the active site of thymidylate synthase ThyX
Published as BJ Immediate Publication 15 January 2014, doi:10.1042/BJ20131567
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The author has paid for access to this article to be freely available Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies
Published as BJ Immediate Publication 17 January 2014, doi:10.1042/BJ20131399
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Frataxin-bypassing Isu1: characterization of the bypass activity in cells and mitochondria
Published as BJ Immediate Publication 16 January 2014, doi:10.1042/BJ20131273
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Functional role of evolutionarily highly conserved residues, N-glycosylation level and domains of the Leishmania miltefosine transporter-Cdc50 subunit
Published as BJ Immediate Publication 21 January 2014, doi:10.1042/BJ20131318
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Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states
Published as BJ Immediate Publication 24 January 2014, doi:10.1042/BJ20131668
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C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage
Published as BJ Immediate Publication 20 January 2014, doi:10.1042/BJ20131378
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Decrease in cytochrome c oxidase reserve capacity diminishes robustness of Drosophila melanogaster and shortens lifespan
Published as BJ Immediate Publication 21 January 2014, doi:10.1042/BJ20131370
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Niemann–Pick disease type C2 protein induces triglyceride accumulation in silkworm and mammalian cell lines
Published as BJ Immediate Publication 20 January 2014, doi:10.1042/BJ20130876
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Singlet oxygen effects on lipid membranes: implications for the mechanism of action of broad-spectrum viral fusion inhibitors
Published as BJ Immediate Publication 24 January 2014, doi:10.1042/BJ20131058
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The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells
Published as BJ Immediate Publication 27 January 2014, doi:10.1042/BJ20130894
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Primary structural features of SR-like protein acinusS govern the phosphorylation mechanism by SRPK2
Published as BJ Immediate Publication 21 January 2014, doi:10.1042/BJ20131091
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Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2
Published as BJ Immediate Publication 20 January 2014, doi:10.1042/BJ20130558
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Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER
Published as BJ Immediate Publication 16 January 2014, doi:10.1042/BJ20130642
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Volume 458

The Cdc48–Vms1 complex maintains 26S proteasome architecture
Published as BJ Immediate Publication 19 December 2013, doi:10.1042/BJ20131161
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CREB phosphorylation at Ser133 regulates transcription via distinct mechanisms downstream of cAMP and MAPK signalling
Published as BJ Immediate Publication 8 January 2014, doi:10.1042/BJ20131115
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Novel evidence for the specific interaction between cholesterol and α-haemolysin of Escherichia coli
Published as BJ Immediate Publication 19 December 2013, doi:10.1042/BJ20131432
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Insulin-stimulated leptin secretion requires calcium and PI3K/Akt activation
Published as BJ Immediate Publication 10 January 2014, doi:10.1042/BJ20131176
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The author has paid for access to this article to be freely available Structural and functional characterization of NanU, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling Bacteroidetes species
Published as BJ Immediate Publication 19 December 2013, doi:10.1042/BJ20131415
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A dual-targeted aminoacyl-tRNA synthetase in Plasmodium falciparum charges cytosolic and apicoplast tRNACys
Published as BJ Immediate Publication 16 January 2014, doi:10.1042/BJ20131451
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The author has paid for access to this article to be freely available Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12
Published as BJ Immediate Publication 10 January 2014, doi:10.1042/BJ20131429
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The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity
Published as BJ Immediate Publication 6 January 2014, doi:10.1042/BJ20131288
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Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases1
Published as BJ Immediate Publication 7 January 2014, doi:10.1042/BJ20131103
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Effects of alternative splicing on the function of bestrophin-1 calcium-activated chloride channels
Published as BJ Immediate Publication 17 December 2013, doi:10.1042/BJ20121546
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The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h
Published as BJ Immediate Publication 10 December 2013, doi:10.1042/BJ20130979
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A purine nucleoside phosphorylase in Solanum tuberosum L. (potato) with specificity for cytokinins contributes to the duration of tuber endodormancy
Published as BJ Immediate Publication 10 December 2013, doi:10.1042/BJ20130792
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A transmembrane serine residue in the Rot1 protein is essential for yeast cell viability
Published as BJ Immediate Publication 5 December 2013, doi:10.1042/BJ20131306
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Physiological expression of the PI3K-activating mutation Pik3caH1047R combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice
Published as BJ Immediate Publication 9 December 2013, doi:10.1042/BJ20131412
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Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release
Published as BJ Immediate Publication 13 December 2013, doi:10.1042/BJ20131386
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Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices
Published as BJ Immediate Publication 18 December 2013, doi:10.1042/BJ20131463
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Pyruvate kinases have an intrinsic and conserved decarboxylase activity
Published as BJ Immediate Publication 13 December 2013, doi:10.1042/BJ20130790
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Phosphorylation of Arabidopsis transketolase at Ser428 provides a potential paradigm for the metabolic control of chloroplast carbon metabolism
Published as BJ Immediate Publication 13 December 2013, doi:10.1042/BJ20130631
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GPI (glycosylphosphatidylinositol)-linked aspartyl proteases regulate vacuole homoeostasis in Candida glabrata
Published as BJ Immediate Publication 17 December 2013, doi:10.1042/BJ20130757
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Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors
Published as BJ Immediate Publication 24 December 2013, doi:10.1042/BJ20130818
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RAD-6: pyrimidine synthesis and radiation sensitivity in Caenorhabditis elegans
Published as BJ Immediate Publication 22 November 2013, doi:10.1042/BJ20131085
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Sequestration of the abrin A chain to the nucleus by BASP1 increases the resistance of cells to abrin toxicity
Published as BJ Immediate Publication 19 December 2013, doi:10.1042/BJ20131110
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A structure-guided fragment-based approach for the discovery of allosteric inhibitors targeting the lipophilic binding site of transcription factor EthR
Published as BJ Immediate Publication 6 December 2013, doi:10.1042/BJ20131127
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Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses
Published as BJ Immediate Publication 19 December 2013, doi:10.1042/BJ20131516
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Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum
Published as BJ Immediate Publication 11 December 2013, doi:10.1042/BJ20130719
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The Escherichia coli RNA processing and degradation machinery is compartmentalized within an organized cellular network
Published as BJ Immediate Publication 25 November 2013, doi:10.1042/BJ20131287
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Dynamics of mitochondrial Ca2+ uptake in MICU1-knockdown cells
Published as BJ Immediate Publication 9 December 2013, doi:10.1042/BJ20131025
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The author has paid for access to this article to be freely available Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity
Published as BJ Immediate Publication 3 December 2013, doi:10.1042/BJ20131324
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Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion
Published as BJ Immediate Publication 22 November 2013, doi:10.1042/BJ20131186
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c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions
Published as BJ Immediate Publication 22 November 2013, doi:10.1042/BJ20130527
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Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor
Published as BJ Immediate Publication 14 November 2013, doi:10.1042/BJ20130685
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Phosphorylation of bacterial-type phosphoenolpyruvate carboxylase by a Ca2+-dependent protein kinase suggests a link between Ca2+ signalling and anaplerotic pathway control in developing castor oil seeds
Published as BJ Immediate Publication 25 November 2013, doi:10.1042/BJ20131191
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Structure of RDE-4 dsRBDs and mutational studies provide insights into dsRNA recognition in the Caenorhabditis elegans RNAi pathway
Published as BJ Immediate Publication 21 November 2013, doi:10.1042/BJ20131347
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Dynamics of Gαq-protein–p63RhoGEF interaction and its regulation by RGS2
Published as BJ Immediate Publication 4 December 2013, doi:10.1042/BJ20130782
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Mammalian sterile 20-like kinase 1/2 inhibits the Wnt/β-catenin signalling pathway by directly binding casein kinase 1ε
Published as BJ Immediate Publication 4 November 2013, doi:10.1042/BJ20130986
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ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene
Published as BJ Immediate Publication 1 November 2013, doi:10.1042/BJ20130628
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Volume 457

Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
Published as BJ Immediate Publication 13 November 2013, doi:10.1042/BJ20131270
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Secret of the major birch pollen allergen Bet v 1: identification of the physiological ligand
Published as BJ Immediate Publication 30 October 2013, doi:10.1042/BJ20130413
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A novel protein, Pho92, has a conserved YTH domain and regulates phosphate metabolism by decreasing the mRNA stability of PHO4 in Saccharomyces cerevisiae
Published as BJ Immediate Publication 8 November 2013, doi:10.1042/BJ20130862
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The cytokine-induced conformational switch of nuclear factor κB p65 is mediated by p65 phosphorylation
Published as BJ Immediate Publication 31 October 2013, doi:10.1042/BJ20130780
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A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)
Published as BJ Immediate Publication 31 October 2013, doi:10.1042/BJ20131142
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The author has paid for access to this article to be freely available Four-and-a-half LIM domains proteins are novel regulators of the protein kinase D pathway in cardiac myocytes
Published as BJ Immediate Publication 13 November 2013, doi:10.1042/BJ20131026
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Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH
Published as BJ Immediate Publication 12 November 2013, doi:10.1042/BJ20130960
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The author has paid for access to this article to be freely available RAM function is dependent on Kapβ2-mediated nuclear entry
Published as BJ Immediate Publication 7 November 2013, doi:10.1042/BJ20131359
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The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
Published as BJ Immediate Publication 8 November 2013, doi:10.1042/BJ20130155
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The author has paid for access to this article to be freely available Bisubstrate UDP–peptide conjugates as human O-GlcNAc transferase inhibitors
Published as BJ Immediate Publication 21 November 2013, doi:10.1042/BJ20131272
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SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct
Published as BJ Immediate Publication 23 October 2013, doi:10.1042/BJ20130654
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Signal-peptide-mediated translocation is regulated by a p97–AIRAPL complex
Published as BJ Immediate Publication 25 October 2013, doi:10.1042/BJ20130710
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Native oligomerization determines the mode of action and biological activities of human cathelicidin LL-37
Published as BJ Immediate Publication 14 October 2013, doi:10.1042/BJ20131048
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A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17
Published as BJ Immediate Publication 17 October 2013, doi:10.1042/BJ20131213
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Structural insights into the small G-protein Arl13B and implications for Joubert syndrome
Published as BJ Immediate Publication 30 October 2013, doi:10.1042/BJ20131097
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Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5
Published as BJ Immediate Publication 15 October 2013, doi:10.1042/BJ20130827
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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
Published as BJ Immediate Publication 10 October 2013, doi:10.1042/BJ20131174
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Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity
Published as BJ Immediate Publication 25 October 2013, doi:10.1042/BJ20130196
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Characterization of the recombinant Candida albicans β-1,2-mannosyltransferase that initiates the β-mannosylation of cell wall phosphopeptidomannan
Published as BJ Immediate Publication 21 October 2013, doi:10.1042/BJ20131012
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Loss of TRPML1 promotes production of reactive oxygen species: is oxidative damage a factor in mucolipidosis type IV?
Published as BJ Immediate Publication 6 November 2013, doi:10.1042/BJ20130647
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RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function
Published as BJ Immediate Publication 10 October 2013, doi:10.1042/BJ20131227
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A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr286, not Thr288
Published as BJ Immediate Publication 17 October 2013, doi:10.1042/BJ20130461
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Functional characterization of the trypanosome translational repressor SCD6
Published as BJ Immediate Publication 3 October 2013, doi:10.1042/BJ20130747
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Down-regulation of cyclin G2 by insulin, IGF-I (insulin-like growth factor 1) and X10 (AspB10 insulin): role in mitogenesis
Published as BJ Immediate Publication 24 September 2013, doi:10.1042/BJ20130490
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PCSK9 acts as a chaperone for the LDL receptor in the endoplasmic reticulum
Published as BJ Immediate Publication 22 October 2013, doi:10.1042/BJ20130930
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Ligand binding and complex formation of galectin-3 is modulated by pH variations
Published as BJ Immediate Publication 22 October 2013, doi:10.1042/BJ20130933
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Redox regulation of chloroplastic G6PDH activity by thioredoxin occurs through structural changes modifying substrate accessibility and cofactor binding
Published as BJ Immediate Publication 1 October 2013, doi:10.1042/BJ20130337
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The calmodulin-like protein CML43 functions as a salicylic-acid-inducible root-specific Ca2+ sensor in Arabidopsis
Published as BJ Immediate Publication 9 October 2013, doi:10.1042/BJ20131080
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Extended interaction network of procollagen C-proteinase enhancer-1 in the extracellular matrix
Published as BJ Immediate Publication 14 October 2013, doi:10.1042/BJ20130295
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The miR-19a/b family positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1
Published as BJ Immediate Publication 14 October 2013, doi:10.1042/BJ20130833
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The author has paid for access to this article to be freely available The regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylation
Published as BJ Immediate Publication 14 October 2013, doi:10.1042/BJ20130963
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The author has paid for access to this article to be freely available Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO
Published as BJ Immediate Publication 23 October 2013, doi:10.1042/BJ20130753
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The author has paid for access to this article to be freely available Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
Published as BJ Immediate Publication 30 October 2013, doi:10.1042/BJ20131152
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Volume 456

Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties
Published as BJ Immediate Publication 23 September 2013, doi:10.1042/BJ20130788
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Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling
Published as BJ Immediate Publication 17 September 2013, doi:10.1042/BJ20130740
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The author has paid for access to this article to be freely available Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid
Published as BJ Immediate Publication 24 September 2013, doi:10.1042/BJ20131003
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Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle
Published as BJ Immediate Publication 30 September 2013, doi:10.1042/BJ20130807
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The hydrogen-peroxide-induced radical behaviour in human cytochrome c–phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant
Published as BJ Immediate Publication 8 October 2013, doi:10.1042/BJ20130758
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NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
Published as BJ Immediate Publication 4 October 2013, doi:10.1042/BJ20131163
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Regulatory T-cells and cAMP suppress effector T-cells independently of PKA–CREM/ICER: a potential role for Epac
Published as BJ Immediate Publication 5 September 2013, doi:10.1042/BJ20130064
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Cardioprotective 3′,4′-dihydroxyflavonol attenuation of JNK and p38MAPK signalling involves CaMKII inhibition
Published as BJ Immediate Publication 16 September 2013, doi:10.1042/BJ20121538
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Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production
Published as BJ Immediate Publication 11 September 2013, doi:10.1042/BJ20130755
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The ubiquitin–proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic β-cells
Published as BJ Immediate Publication 12 September 2013, doi:10.1042/BJ20130262
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Regulation of trehalase expression inhibits apoptosis in diapause cysts of Artemia
Published as BJ Immediate Publication 25 September 2013, doi:10.1042/BJ20131020
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The author has paid for access to this article to be freely available FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways
Published as BJ Immediate Publication 11 September 2013, doi:10.1042/BJ20131101
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Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation
Published as BJ Immediate Publication 16 September 2013, doi:10.1042/BJ20130148
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C-24-methylation of 26-fluorocycloartenols by recombinant sterol C-24-methyltransferase from soybean: evidence for channel switching and its phylogenetic implications
Published as BJ Immediate Publication 11 September 2013, doi:10.1042/BJ20121818
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Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion
Published as BJ Immediate Publication 9 September 2013, doi:10.1042/BJ20130538
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Mycobacterium smegmatis Ku binds DNA without free ends
Published as BJ Immediate Publication 24 September 2013, doi:10.1042/BJ20130749
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Complex contributions of fibronectin to initiation and maturation of microfibrils
Published as BJ Immediate Publication 27 September 2013, doi:10.1042/BJ20130699
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The author has paid for access to this article to be freely available Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex
Published as BJ Immediate Publication 10 September 2013, doi:10.1042/BJ20130100
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Analysis of Arabidopsis thioredoxin-h isotypes identifies discrete domains that confer specific structural and functional properties
Published as BJ Immediate Publication 5 September 2013, doi:10.1042/BJ20130618
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The synaptotagmin 1 linker may function as an electrostatic zipper that opens for docking but closes for fusion pore opening
Published as BJ Immediate Publication 4 September 2013, doi:10.1042/BJ20130949
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Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells
Published as BJ Immediate Publication 30 August 2013, doi:10.1042/BJ20130418
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Regulation of the transcriptional activation of the androgen receptor by the UXT-binding protein VHL
Published as BJ Immediate Publication 21 August 2013, doi:10.1042/BJ20121711
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The air–water interface determines the outcome of seeding during amyloidogenesis
Published as BJ Immediate Publication 10 September 2013, doi:10.1042/BJ20130605
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On the catalytic mechanism of dimeric dUTPases
Published as BJ Immediate Publication 4 September 2013, doi:10.1042/BJ20130796
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Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase
Published as BJ Immediate Publication 16 August 2013, doi:10.1042/BJ20130670
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Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus
Published as BJ Immediate Publication 20 August 2013, doi:10.1042/BJ20130123
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PKCδ as a regulator for TGF-β-stimulated connective tissue growth factor production in human hepatocarcinoma (HepG2) cells
Published as BJ Immediate Publication 29 August 2013, doi:10.1042/BJ20130744
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Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
Published as BJ Immediate Publication 12 August 2013, doi:10.1042/BJ20121772
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The author has paid for access to this article to be freely available Investigating the function of [2Fe–2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential
Published as BJ Immediate Publication 27 August 2013, doi:10.1042/BJ20130606
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Volume 455

Identification of a specific one amino acid change in recombinant human transglutaminase 2 that regulates its activity and calcium sensitivity
Published as BJ Immediate Publication 13 August 2013, doi:10.1042/BJ20130696
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Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus
Published as BJ Immediate Publication 29 July 2013, doi:10.1042/BJ20130540
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Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes
Published as BJ Immediate Publication 22 July 2013, doi:10.1042/BJ20130430
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A novel fluorescence assay and catalytic properties of Crh1 and Crh2 yeast cell wall transglycosylases
Published as BJ Immediate Publication 6 August 2013, doi:10.1042/BJ20130354
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Lys1110 of TRPM2 is critical for channel activation
Published as BJ Immediate Publication 19 August 2013, doi:10.1042/BJ20130303
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Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function
Published as BJ Immediate Publication 27 August 2013, doi:10.1042/BJ20130562
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Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy
Published as BJ Immediate Publication 27 August 2013, doi:10.1042/BJ20130597
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Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction
Published as BJ Immediate Publication 5 August 2013, doi:10.1042/BJ20130259
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Completing the folate biosynthesis pathway in Plasmodium falciparum: p-aminobenzoate is produced by a highly divergent promiscuous aminodeoxychorismate lyase
Published as BJ Immediate Publication 19 August 2013, doi:10.1042/BJ20130896
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Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload
Published as BJ Immediate Publication 8 August 2013, doi:10.1042/BJ20130029
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The reduction in sigma-promoter recognition flexibility as induced by core RNAP is required for sigma to discern the optimal promoter spacing
Published as BJ Immediate Publication 22 July 2013, doi:10.1042/BJ20130576
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Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle
Published as BJ Immediate Publication 1 August 2013, doi:10.1042/BJ20130644
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TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt
Published as BJ Immediate Publication 5 August 2013, doi:10.1042/BJ20130760
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Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress
Published as BJ Immediate Publication 2 August 2013, doi:10.1042/BJ20130579
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The author has paid for access to this article to be freely available A mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)
Published as BJ Immediate Publication 7 August 2013, doi:10.1042/BJ20130483
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Characterization of inflamin, the first member of a new family of snake venom proteins that induces inflammation
Published as BJ Immediate Publication 8 July 2013, doi:10.1042/BJ20130599
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Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4
Published as BJ Immediate Publication 10 July 2013, doi:10.1042/BJ20130281
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Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death
Published as BJ Immediate Publication 1 July 2013, doi:10.1042/BJ20130556
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The carbonylation and covalent dimerization of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity is inhibited by the radical scavenger tempol
Published as BJ Immediate Publication 16 July 2013, doi:10.1042/BJ20130180
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AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex
Published as BJ Immediate Publication 29 July 2013, doi:10.1042/BJ20130359
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The mitochondrial carrier Rim2 co-imports pyrimidine nucleotides and iron
Published as BJ Immediate Publication 26 June 2013, doi:10.1042/BJ20130144
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The author has paid for access to this article to be freely available The central role of mosquito cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling
Published as BJ Immediate Publication 11 July 2013, doi:10.1042/BJ20130577
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Sorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junction
Published as BJ Immediate Publication 4 July 2013, doi:10.1042/BJ20121755
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The author has paid for access to this article to be freely available EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein
Published as BJ Immediate Publication 19 July 2013, doi:10.1042/BJ20130126
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Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop
Published as BJ Immediate Publication 2 August 2013, doi:10.1042/BJ20130669
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Volume 454

Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies
Published as BJ Immediate Publication 20 June 2013, doi:10.1042/BJ20130389
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An aromatic amino acid in the coiled-coil 1 domain plays a crucial role in the auto-inhibitory mechanism of STIM1
Published as BJ Immediate Publication 25 June 2013, doi:10.1042/BJ20130292
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Chemical suppression of an oncogenic splicing variant of AIMP2 induces tumour regression
Published as BJ Immediate Publication 1 July 2013, doi:10.1042/BJ20130550
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Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases
Published as BJ Immediate Publication 28 June 2013, doi:10.1042/BJ20130563
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Zinc co-ordination by the DHHC cysteine-rich domain of the palmitoyltransferase Swf1
Published as BJ Immediate Publication 24 June 2013, doi:10.1042/BJ20121693
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Structural basis for phosphorylation-triggered autophagic clearance of Salmonella
Published as BJ Immediate Publication 28 June 2013, doi:10.1042/BJ20121907
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Formation of assemblies on cell membranes by secreted proteins: molecular studies of free λ light chain aggregates found on the surface of myeloma cells
Published as BJ Immediate Publication 4 July 2013, doi:10.1042/BJ20130575
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Mercury increases water permeability of a plant aquaporin through a non-cysteine-related mechanism
Published as BJ Immediate Publication 3 July 2013, doi:10.1042/BJ20130377
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The author has paid for access to this article to be freely available Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants
Published as BJ Immediate Publication 4 July 2013, doi:10.1042/BJ20121750
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Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production
Published as BJ Immediate Publication 10 July 2013, doi:10.1042/BJ20130554
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A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism
Published as BJ Immediate Publication 9 July 2013, doi:10.1042/BJ20130516
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An antioxidant role for catecholate siderophores in Salmonella
Published as BJ Immediate Publication 28 June 2013, doi:10.1042/BJ20121771
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Channel-mediated lactic acid transport: a novel function for aquaglyceroporins in bacteria
Published as BJ Immediate Publication 25 June 2013, doi:10.1042/BJ20130388
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A novel interplay between the ubiquitin–proteasome system and serine proteases during Drosophila development
Published as BJ Immediate Publication 28 June 2013, doi:10.1042/BJ20130040
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SATP (YaaH), a succinate–acetate transporter protein in Escherichia coli
Published as BJ Immediate Publication 11 July 2013, doi:10.1042/BJ20130412
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The author has paid for access to this article to be freely available Proteolytic processing of QSOX1A ensures efficient secretion of a potent disulfide catalyst
Published as BJ Immediate Publication 28 May 2013, doi:10.1042/BJ20130360
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Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance
Published as BJ Immediate Publication 12 June 2013, doi:10.1042/BJ20130317
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ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors
Published as BJ Immediate Publication 18 June 2013, doi:10.1042/BJ20130282
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Metabolic phenotypes of Saccharomyces cerevisiae mutants with altered trehalose 6-phosphate dynamics
Published as BJ Immediate Publication 14 June 2013, doi:10.1042/BJ20130587
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Cross-functionalities of Bacillus deacetylases involved in bacillithiol biosynthesis and bacillithiol-S-conjugate detoxification pathways
Published as BJ Immediate Publication 11 June 2013, doi:10.1042/BJ20130415
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Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts
Published as BJ Immediate Publication 17 June 2013, doi:10.1042/BJ20130414
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A general anaesthetic propofol inhibits aquaporin-4 in the presence of Zn2+
Published as BJ Immediate Publication 17 June 2013, doi:10.1042/BJ20130046
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The author has paid for access to this article to be freely available Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells
Published as BJ Immediate Publication 19 June 2013, doi:10.1042/BJ20130481
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A GPI anchor explains the unique biological features of the common NKG2D-ligand allele MICA*008
Published as BJ Immediate Publication 18 June 2013, doi:10.1042/BJ20130194
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Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera
Published as BJ Immediate Publication 26 June 2013, doi:10.1042/BJ20130636
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Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling
Published as BJ Immediate Publication 12 June 2013, doi:10.1042/BJ20121799
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The physical interaction of Mcm10 with Cdc45 modulates their DNA-binding properties
Published as BJ Immediate Publication 10 June 2013, doi:10.1042/BJ20130059
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The use of alternative polyadenylation sites renders integrin β1 (Itgb1) mRNA isoforms with differential stability during mammary gland development
Published as BJ Immediate Publication 21 June 2013, doi:10.1042/BJ20130062
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Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Published as BJ Immediate Publication 3 June 2013, doi:10.1042/BJ20121863
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The author has paid for access to this article to be freely available Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization
Published as BJ Immediate Publication 12 June 2013, doi:10.1042/BJ20130488
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Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3
Published as BJ Immediate Publication 3 June 2013, doi:10.1042/BJ20130193
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Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain–domain interactions
Published as BJ Immediate Publication 31 May 2013, doi:10.1042/BJ20130328
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The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53–N-WASP interaction in epithelial cells
Published as BJ Immediate Publication 10 June 2013, doi:10.1042/BJ20121701
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Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate
Published as BJ Immediate Publication 4 June 2013, doi:10.1042/BJ20130153
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Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits
Published as BJ Immediate Publication 31 May 2013, doi:10.1042/BJ20130297
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Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes
Published as BJ Immediate Publication 4 June 2013, doi:10.1042/BJ20130323
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Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification
Published as BJ Immediate Publication 11 June 2013, doi:10.1042/BJ20121656
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Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family
Published as BJ Immediate Publication 10 June 2013, doi:10.1042/BJ20130552
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Volume 453

A highly efficient peptide substrate for EGFR activates the kinase by inducing aggregation
Published as BJ Immediate Publication 5 June 2013, doi:10.1042/BJ20130537
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The author has paid for access to this article to be freely available Analysing the visible conformational substates of the FK506-binding protein FKBP12
Published as BJ Immediate Publication 21 May 2013, doi:10.1042/BJ20130276
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The author has paid for access to this article to be freely available p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival
Published as BJ Immediate Publication 22 May 2013, doi:10.1042/BJ20121829
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The folding capacity of the mature domain of the dual-targeted plant tRNA nucleotidyltransferase influences organelle selection
Published as BJ Immediate Publication 28 May 2013, doi:10.1042/BJ20121577
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PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains
Published as BJ Immediate Publication 20 May 2013, doi:10.1042/BJ20121528
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Molecular determinants of co- and post-translational N-glycosylation of type I transmembrane peptides
Published as BJ Immediate Publication 29 May 2013, doi:10.1042/BJ20130028
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The author has paid for access to this article to be freely available The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain
Published as BJ Immediate Publication 26 April 2013, doi:10.1042/BJ20130133
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Multilevel functional and structural defects induced by two pathogenic mitochondrial tRNA mutations
Published as BJ Immediate Publication 1 May 2013, doi:10.1042/BJ20130294
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Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A
Published as BJ Immediate Publication 14 May 2013, doi:10.1042/BJ20130263
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Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46
Published as BJ Immediate Publication 28 May 2013, doi:10.1042/BJ20130030
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The author has paid for access to this article to be freely available CRISPR interference: a structural perspective
Published on the Internet 28 June 2013, doi:10.1042/BJ20130316
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Structural characterization of amorphous calcium carbonate-binding protein: an insight into the mechanism of amorphous calcium carbonate formation
Published as BJ Immediate Publication 7 May 2013, doi:10.1042/BJ20130285
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STIM1 negatively regulates Ca2+ release from the sarcoplasmic reticulum in skeletal myotubes
Published as BJ Immediate Publication 14 May 2013, doi:10.1042/BJ20130178
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RACK1 (receptor for activated C-kinase 1) interacts with FBW2 (F-box and WD-repeat domain-containing 2) to up-regulate GCM1 (glial cell missing 1) stability and placental cell migration and invasion
Published as BJ Immediate Publication 7 May 2013, doi:10.1042/BJ20130175
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SUMOylation is a regulator of the translocation of Jak2 between nucleus and cytosol
Published as BJ Immediate Publication 15 April 2013, doi:10.1042/BJ20121375
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Tailoring GalNAcα1-3Galβ-specific lectins from a multi-specific fungal galectin: dramatic change of carbohydrate specificity by a single amino-acid substitution
Published as BJ Immediate Publication 23 April 2013, doi:10.1042/BJ20121901
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Mechanistic insights into small RNA recognition and modification by the HEN1 methyltransferase
Published as BJ Immediate Publication 29 April 2013, doi:10.1042/BJ20121699
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βTrCP interacts with the ubiquitin-dependent endocytosis motif of the GH receptor in an unconventional manner
Published as BJ Immediate Publication 22 April 2013, doi:10.1042/BJ20121843
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New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases
Published as BJ Immediate Publication 9 April 2013, doi:10.1042/BJ20121769
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Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E
Published as BJ Immediate Publication 29 April 2013, doi:10.1042/BJ20130391
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Lipin1 regulates PPARγ transcriptional activity
Published as BJ Immediate Publication 30 April 2013, doi:10.1042/BJ20121598
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Evidence of a novel role for Pygopus in rRNA transcription
Published as BJ Immediate Publication 22 March 2013, doi:10.1042/BJ20121667
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The author has paid for access to this article to be freely available Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity
Published as BJ Immediate Publication 16 April 2013, doi:10.1042/BJ20130049
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Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans
Published as BJ Immediate Publication 5 April 2013, doi:10.1042/BJ20130166
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The author has paid for access to this article to be freely available Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies
Published as BJ Immediate Publication 5 April 2013, doi:10.1042/BJ20121742
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The author has paid for access to this article to be freely available Ube2W conjugates ubiquitin to α-amino groups of protein N-termini
Published as BJ Immediate Publication 8 April 2013, doi:10.1042/BJ20130244
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Volume 452

Structural model of a putrescine-cadaverine permease from Trypanosoma cruzi predicts residues vital for transport and ligand binding
Published as BJ Immediate Publication 28 March 2013, doi:10.1042/BJ20130350
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Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development
Published as BJ Immediate Publication 3 April 2013, doi:10.1042/BJ20130124
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TMEM16A–TMEM16B chimaeras to investigate the structure–function relationship of calcium-activated chloride channels
Published as BJ Immediate Publication 10 April 2013, doi:10.1042/BJ20130348
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The author has paid for access to this article to be freely available Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum
Published as BJ Immediate Publication 2 April 2013, doi:10.1042/BJ20121694
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Co-operative function and mutual stabilization of the half ATP-binding cassette transporters HAF-4 and HAF-9 in Caenorhabditis elegans
Published as BJ Immediate Publication 5 March 2013, doi:10.1042/BJ20130115
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An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins
Published as BJ Immediate Publication 4 April 2013, doi:10.1042/BJ20121824
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Differential regulation of glucose transport activity in yeast by specific cAMP signatures
Published as BJ Immediate Publication 15 March 2013, doi:10.1042/BJ20121736
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The author has paid for access to this article to be freely available Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors
Published as BJ Immediate Publication 15 April 2013, doi:10.1042/BJ20130342
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PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli
Published as BJ Immediate Publication 2 April 2013, doi:10.1042/BJ20121886
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Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin)
Published as BJ Immediate Publication 2 April 2013, doi:10.1042/BJ20121277
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GlgS, described previously as a glycogen synthesis control protein, negatively regulates motility and biofilm formation in Escherichia coli
Published as BJ Immediate Publication 28 March 2013, doi:10.1042/BJ20130154
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Formation of a tyrosine adduct involved in lignin degradation by Trametopsis cervina lignin peroxidase: a novel peroxidase activation mechanism
Published as BJ Immediate Publication 3 April 2013, doi:10.1042/BJ20130251
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Membrane topology of yeast alkaline ceramidase YPC1
Published as BJ Immediate Publication 27 February 2013, doi:10.1042/BJ20130085
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Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells
Published as BJ Immediate Publication 4 April 2013, doi:10.1042/BJ20121873
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Crystal structures of glycoside hydrolase family 3 β-glucosidase 1 from Aspergillus aculeatus
Published as BJ Immediate Publication 28 March 2013, doi:10.1042/BJ20130054
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The author has paid for access to this article to be freely available Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20130269
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Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4
Published as BJ Immediate Publication 20 March 2013, doi:10.1042/BJ20121778
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Single-strand promoter traps for bacterial RNA polymerase
Published as BJ Immediate Publication 22 March 2013, doi:10.1042/BJ20130069
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TgrC1 mediates cell–cell adhesion by interacting with TgrB1 via mutual IPT/TIG domains during development of Dictyostelium discoideum
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20121674
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Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement
Published as BJ Immediate Publication 18 March 2013, doi:10.1042/BJ20121880
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microRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1
Published as BJ Immediate Publication 13 March 2013, doi:10.1042/BJ20120680
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The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20121902
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A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation
Published as BJ Immediate Publication 18 March 2013, doi:10.1042/BJ20121578
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The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII
Published as BJ Immediate Publication 5 March 2013, doi:10.1042/BJ20121200
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Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121580
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Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus
Published as BJ Immediate Publication 4 March 2013, doi:10.1042/BJ20121870
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mRNA encoding WAVE–Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration
Published as BJ Immediate Publication 4 March 2013, doi:10.1042/BJ20121803
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The author has paid for access to this article to be freely available Characterization of a pre-export enzyme–chaperone complex on the twin-arginine transport pathway
Published as BJ Immediate Publication 1 March 2013, doi:10.1042/BJ20121832
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Nuclear export factor 3 is involved in regulating the expression of TGF-β3 in an mRNA export activity-independent manner in mouse Sertoli cells
Published as BJ Immediate Publication 25 February 2013, doi:10.1042/BJ20121006
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FSL-61 is a 6-nitroquinolone fluorogenic probe for one-electron reductases in hypoxic cells
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20121695
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Proteomic analysis and molecular modelling characterize the iron-regulatory protein haemojuvelin/repulsive guidance molecule c
Published as BJ Immediate Publication 6 March 2013, doi:10.1042/BJ20121845
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ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins
Published as BJ Immediate Publication 5 March 2013, doi:10.1042/BJ20121558
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BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20130147
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Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation
Published as BJ Immediate Publication 26 February 2013, doi:10.1042/BJ20121140
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FGF-2 prevents cancer cells from ER stress-mediated apoptosis via enhancing proteasome-mediated Nck degradation
Published as BJ Immediate Publication 1 March 2013, doi:10.1042/BJ20121671
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Protein recognition of the S23906-1–DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Published as BJ Immediate Publication 14 February 2013, doi:10.1042/BJ20120860
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Protein disulfide-isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity
Published as BJ Immediate Publication 11 March 2013, doi:10.1042/BJ20130298
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Volume 451

The author has paid for access to this article to be freely available Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport
Published as BJ Immediate Publication 21 February 2013, doi:10.1042/BJ20121745
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PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121344
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Unexpected weak magnetic exchange coupling between haem and non-haem iron in the catalytic site of nitric oxide reductase (NorBC) from Paracoccus denitrificans
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121406
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ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours
Published as BJ Immediate Publication 22 January 2013, doi:10.1042/BJ20120873
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Structure–function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121622
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Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency
Published as BJ Immediate Publication 26 February 2013, doi:10.1042/BJ20130041
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The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
Published as BJ Immediate Publication 27 February 2013, doi:10.1042/BJ20121651
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Prediction of hammerhead ribozyme intracellular activity with the catalytic core fingerprint
Published as BJ Immediate Publication 19 February 2013, doi:10.1042/BJ20121761
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The author has paid for access to this article to be freely available DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα
Published as BJ Immediate Publication 12 February 2013, doi:10.1042/BJ20121085
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Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121717
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Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter
Published as BJ Immediate Publication 1 February 2013, doi:10.1042/BJ20121506
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Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1
Published as BJ Immediate Publication 6 February 2013, doi:10.1042/BJ20121819
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The author has paid for access to this article to be freely available Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain
Published as BJ Immediate Publication 2 January 2013, doi:10.1042/BJ20121600
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The author has paid for access to this article to be freely available The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability
Published as BJ Immediate Publication 11 February 2013, doi:10.1042/BJ20130026
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Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment
Published as BJ Immediate Publication 1 February 2013, doi:10.1042/BJ20121447
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Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity
Published as BJ Immediate Publication 4 February 2013, doi:10.1042/BJ20121715
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Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1
Published as BJ Immediate Publication 7 February 2013, doi:10.1042/BJ20121669
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The author has paid for access to this article to be freely available V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins
Published as BJ Immediate Publication 4 February 2013, doi:10.1042/BJ20121839
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Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells
Published as BJ Immediate Publication 31 January 2013, doi:10.1042/BJ20121553
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Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example
Published as BJ Immediate Publication 11 February 2013, doi:10.1042/BJ20121798
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Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)
Published as BJ Immediate Publication 29 January 2013, doi:10.1042/BJ20120627
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Prohepcidin binds to the HAMP promoter and autoregulates its own expression
Published as BJ Immediate Publication 7 February 2013, doi:10.1042/BJ20121466
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A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery
Published as BJ Immediate Publication 12 February 2013, doi:10.1042/BJ20121418
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Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121871
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The author has paid for access to this article to be freely available The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
Akihito Ohta, Frances‑Rose Schumacher, Youcef Mehellou, Clare Johnson, Axel Knebel, Thomas J. Macartney, Nicola T. Wood, Dario R. Alessi and Thimo Kurz..........111‑122
Published as BJ Immediate Publication 6 February 2013, doi:10.1042/BJ20121903
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The author has paid for access to this article to be freely available Saltatory formation, sliding and dissolution of ER–PM junctions in migrating cancer cells
Hayley Dingsdale, Emmanuel Okeke, Muhammad Awais, Lee Haynes, David N. Criddle, Robert Sutton and Alexei V. Tepikin..........25‑32
Published as BJ Immediate Publication 16 January 2013, doi:10.1042/BJ20121864
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Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)
Ghazi M. Rahman, Sreejesh Shanker, Nancy E. Lewin, Noemi Kedei, Colin S. Hill, B. V.  Venkataram Prasad, Peter M. Blumberg and Joydip Das..........33‑44
Published as BJ Immediate Publication 4 January 2013, doi:10.1042/BJ20121307
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The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity
Ismayil Tasdelen, Olivier van Beekum, Olena Gorbenko, Veerle Fleskens, Niels J. F. van den Broek, Arjen Koppen, Nicole Hamers, Ruud Berger, Paul J. Coffer, Arjan B. Brenkman and Eric Kalkhoven..........45‑53
Published as BJ Immediate Publication 15 January 2013, doi:10.1042/BJ20121113
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Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus
Alexandra A. Roberts, Sunil V. Sharma, Andrew W. Strankman, Shayla R. Duran, Mamta Rawat and Chris J. Hamilton..........69‑79
Published as BJ Immediate Publication 21 December 2012, doi:10.1042/BJ20121541
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AdE-1, a new inotropic Na+ channel toxin from Aiptasia diaphana, is similar to, yet distinct from, known anemone Na+ channel toxins
Nir Nesher, Eli Shapira, Daniel Sher, Yehu Moran, Liora Tsveyer, Ana Luiza Turchetti‑Maia, Michal Horowitz, Binyamin Hochner and Eliahu Zlotkin..........81‑90
Published as BJ Immediate Publication 28 January 2013, doi:10.1042/BJ20121623
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The author has paid for access to this article to be freely available The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells
Olivia C. Probst, Evren Karayel, Nicole Schida, Elisabeth Nimmerfall, Elisabeth Hehenberger, Verena Puxbaum and Lukas Mach..........91‑99
Published as BJ Immediate Publication 25 January 2013, doi:10.1042/BJ20121422
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HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage
Ji‑hyun Ju, Wonseok Yang, Sunhwa Oh, KeeSoo Nam, Kyung‑min Lee, Dong‑young Noh and Incheol Shin..........123‑134
Published as BJ Immediate Publication 17 January 2013, doi:10.1042/BJ20121716
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Volume 450

The author has paid for access to this article to be freely available Exploring the sequence–structure relationship for amyloid peptides
Kyle L. Morris, Alison Rodger, Matthew R. Hicks, Maya Debulpaep, Joost Schymkowitz, Frederic Rousseau and Louise C. Serpell..........275‑283
Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121773
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The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance
Matthew J. Sale and Simon J. Cook..........285‑294
Published as BJ Immediate Publication 13 December 2012, doi:10.1042/BJ20121212
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Autoimmune disorder phenotypes in Hvcn1-deficient mice
Mari Sasaki, Akihiro Tojo, Yoshifumi Okochi, Nana Miyawaki, Daisuke Kamimura, Akihito Yamaguchi, Masaaki Murakami and Yasushi Okamura..........295‑301
Published as BJ Immediate Publication 12 December 2012, doi:10.1042/BJ20121188
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The author has paid for access to this article to be freely available High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility
Nader T. Amin, A. Katrine Wallis, Stephen A. Wells, Michelle L. Rowe, Richard A. Williamson, Mark J. Howard and Robert B. Freedman..........321‑332
Published as BJ Immediate Publication 12 December 2012, doi:10.1042/BJ20121635
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Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways
Laura van Berge, Josta Kevenaar, Emiel Polder, Agnès Gaudry, Catherine Florentz, Marie Sissler, Marjo S. van der Knaap and Gert C. Scheper..........345‑350
Published as BJ Immediate Publication 10 December 2012, doi:10.1042/BJ20121564
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The author has paid for access to this article to be freely available p90 Ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq-protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists
Emre Amirak, Stephen J. Fuller, Peter H. Sugden and Angela Clerk..........351‑363
Published as BJ Immediate Publication 10 December 2012, doi:10.1042/BJ20121371
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Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells
Tetsuya Kitaguchi, Manami Oya, Yoshiko Wada, Takashi Tsuboi and Atsushi Miyawaki..........365‑373
Published as BJ Immediate Publication 3 January 2013, doi:10.1042/BJ20121022
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Misprocessing and functional arrest of microRNAs by miR-Pirate: roles of miR-378 and miR-17
Zhaoqun Deng, Xiangling Yang, Ling Fang, Zina J. Rutnam and Burton B. Yang..........375‑386
Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20120722
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Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein
Ágnes Telbisz, Csilla Özvegy‑Laczka, Tamás Hegedűs, András Váradi and Balázs Sarkadi..........387‑395
Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20121485
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Identification of an 8-vinyl reductase involved in bacteriochlorophyll biosynthesis in Rhodobacter sphaeroides and evidence for the existence of a third distinct class of the enzyme
Daniel P. Canniffe, Philip J. Jackson, Sarah Hollingshead, Mark J. Dickman and C. Neil Hunter..........397‑405
Published as BJ Immediate Publication 19 December 2012, doi:10.1042/BJ20121723
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Proteomic analysis of Mesembryanthemum crystallinum leaf microsomal fractions finds an imbalance in V-ATPase stoichiometry during the salt-induced transition from C3 to CAM
Cristian Cosentino, Dario Di Silvestre, Elke Fischer‑Schliebs, Ulrike Homann, Antonella De Palma, Claudio Comunian, Pier Luigi Mauri and Gerhard Thiel..........407‑415
Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121087
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The author has paid for access to this article to be freely available Structure and mechanism of the PilF DNA transformation ATPase from Thermus thermophilus
Richard F. Collins, Darin Hassan, Vijaykumar Karuppiah, Angela Thistlethwaite and Jeremy P. Derrick..........417‑425
Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121599
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Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy
Yoshitaka Kimori, Norio Baba and Eisaku Katayama..........23‑35
Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20120412
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Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition
Jakub Kopycki, Elizabeth Wieduwild, Janine Kohlschmidt, Wolfgang Brandt, Anna N. Stepanova, Jose M. Alonso, M. Soledade C. Pedras, Steffen Abel and C. Douglas Grubb..........37‑46
Published as BJ Immediate Publication 15 November 2012, doi:10.1042/BJ20121403
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Parkinson's disease-associated human P5B-ATPase ATP13A2 increases spermidine uptake
Diego P. De La Hera, Gerardo R. Corradi, Hugo P. Adamo and Felicitas De Tezanos Pinto..........47‑53
Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20120739
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A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor
Aurélien Bidaud‑Meynard, Daniela Arma, Said Taouji, Michel Laguerre, Jean Dessolin, Jean Rosenbaum, Eric Chevet and Violaine Moreau..........55‑62
Published as BJ Immediate Publication 27 November 2012, doi:10.1042/BJ20120572
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Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote
William B. Musgrave, Hankuil Yi, Dustin Kline, Jeffrey C. Cameron, Jonathan Wignes, Sanghamitra Dey, Himadri B. Pakrasi and Joseph M. Jez..........63‑72
Published as BJ Immediate Publication 21 November 2012, doi:10.1042/BJ20121332
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Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane
Sonja Huser, Gregor Suri, Pascal Crottet and Martin Spiess..........73‑83
Published as BJ Immediate Publication 29 November 2012, doi:10.1042/BJ20121373
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The author has paid for access to this article to be freely available Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region
Deshun Gong, Fan Yang, Fudong Li, Dandan Qian, Minhao Wu, Zhenhua Shao, Mian Wu, Jihui Wu and Yunyu Shi..........85‑94
Published as BJ Immediate Publication 28 November 2012, doi:10.1042/BJ20121382
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The structure and properties of septin 3: a possible missing link in septin filament formation
Joci N. A. Macedo, Napoleão F. Valadares, Ivo A. Marques, Frederico M. Ferreira, Julio C. P. Damalio, Humberto M. Pereira, Richard C. Garratt and Ana P. U. Araujo..........95‑105
Published as BJ Immediate Publication 19 November 2012, doi:10.1042/BJ20120851
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Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation
Sabine Windhorst, Hongying Lin, Christine Blechner, Werner Fanick, Laura Brandt, Maria A. Brehm and Georg W. Mayr..........115‑125
Published as BJ Immediate Publication 28 November 2012, doi:10.1042/BJ20121524
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Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis
Debajyoti Dutta, Sudipta Bhattacharyya, Amlan Roychowdhury, Rupam Biswas and Amit Kumar Das..........127‑139
Published as BJ Immediate Publication 19 November 2012, doi:10.1042/BJ20121107
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Metal insertion into the molybdenum cofactor: product–substrate channelling demonstrates the functional origin of domain fusion in gephyrin
Abdel A. Belaidi and Guenter Schwarz..........149‑157
Published as BJ Immediate Publication 20 November 2012, doi:10.1042/BJ20121078
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Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active
Sweta Maheshwari, Marina Lavigne, Alicia Contet, Blandine Alberge, Emilie Pihan, Clemens Kocken, Kai Wengelnik, Dominique Douguet, Henri Vial and Rachel Cerdan..........159‑167
Published as BJ Immediate Publication 30 November 2012, doi:10.1042/BJ20121480
Abstract | Full text HTML | Full text PDF | Online Data
The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function
Veena Coothankandaswamy, Selvakumar Elangovan, Nagendra Singh, Puttur D. Prasad, Muthusamy Thangaraju and Vadivel Ganapathy..........169‑178
Published as BJ Immediate Publication 20 November 2012, doi:10.1042/BJ20121248
Abstract | Full text HTML | Full text PDF | Online Data
Identification and properties of a novel variant of NBC4 (Na+/HCO3 co-transporter 4) that is predominantly expressed in the choroid plexus
Hidekazu Fukuda, Taku Hirata, Nobuhiro Nakamura, Akira Kato, Katsumasa Kawahara, Shigeo Wakabayashi, Min‑Hwang Chang, Michael F. Romero and Shigehisa Hirose..........179‑187
Published as BJ Immediate Publication 4 December 2012, doi:10.1042/BJ20121515
Abstract | Full text HTML | Full text PDF | Online Data
Differential configurations involving binding of USF transcription factors and Twist1 regulate Alx3 promoter activity in mesenchymal and pancreatic cells
Patricia García‑Sanz, Antonio Fernández‑Pérez and Mario Vallejo..........199‑208
Published as BJ Immediate Publication 27 November 2012, doi:10.1042/BJ20120962
Abstract | Full text HTML | Full text PDF | Online Data
Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes
Zoran Radić, Trevor Dale, Zrinka Kovarik, Suzana Berend, Edzna Garcia, Limin Zhang, Gabriel Amitai, Carol Green, Božica Radić, Brendan M. Duggan, Dariush Ajami, Julius Rebek and Palmer Taylor..........231‑242
Published as BJ Immediate Publication 6 December 2012, doi:10.1042/BJ20121612
Abstract | Full text HTML | Full text PDF | Online Data
Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity
Liang‑Liang Ruan, Xiao‑Long Zhou, Min Tan and En‑Duo Wang..........243‑252
Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20121493
Abstract | Full text HTML | Full text PDF | Online Data

Volume 449

Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin
Wulin Yang, Xiangxiang Guo, Shermaine Thein, Feng Xu, Shigeki Sugii, Peter W. Baas, George K. Radda and Weiping Han..........605‑612
Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20121121
Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
The CARD plays a critical role in ASC foci formation and inflammasome signalling
Martina Proell, Motti Gerlic, Peter D. Mace, John C. Reed and Stefan J. Riedl..........613‑621
Published as BJ Immediate Publication 31 October 2012, doi:10.1042/BJ20121198
Abstract | Full text HTML | Full text PDF | Online Data
ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement1
Tiziana Guastafierro, Angela Catizone, Roberta Calabrese, Michele Zampieri, Oliviano Martella, Maria Giulia Bacalini, Anna Reale, Maria Di Girolamo, Margherita Miccheli, Dawn Farrar, Elena Klenova, Fabio Ciccarone and Paola Caiafa..........623‑630
Published as BJ Immediate Publication 2 November 2012, doi:10.1042/BJ20121429
Abstract | Full text HTML | Full text PDF | Online Data
Structure and function of the PorB porin from disseminating Neisseria gonorrhoeae
Kornelius Zeth, Vera Kozjak‑Pavlovic, Michaela Faulstich, Martin Fraunholz, Robert Hurwitz, Oliver Kepp and Thomas Rudel..........631‑642
Published as BJ Immediate Publication 25 October 2012, doi:10.1042/BJ20121025
Abstract | Full text HTML | Full text PDF | Online Data
Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins
Tamara D. Skene‑Arnold, Hue Anh Luu, R. Glen Uhrig, Veerle De Wever, Mhairi Nimick, Jason Maynes, Andrea Fong, Michael N. G. James, Laura Trinkle‑Mulcahy, Greg B. Moorhead and Charles F. B. Holmes..........649‑659
Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20120506
Abstract | Full text HTML | Full text PDF | Online Data
Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins
K. Alexa Orr Gandy, Daniel Canals, Mohamad Adada, Masayuki Wada, Patrick Roddy, Ashley J. Snider, Yusuf A. Hannun and Lina M. Obeid..........661‑672
Published as BJ Immediate Publication 29 October 2012, doi:10.1042/BJ20120213
Abstract | Full text HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans
Haitao Wang, Jiaxin Gao, Ada Hang‑Heng Wong, Kangdi Hu, Wanjie Li, Yue Wang and Jianli Sang..........673‑681
Published as BJ Immediate Publication 9 November 2012, doi:10.1042/BJ20120952
Abstract | Full text HTML | Full text PDF | Online Data
Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2
Paolo Mariotti, Enrico Malito, Marco Biancucci, Paola Lo Surdo, Ravi P. N. Mishra, Vincenzo Nardi‑Dei, Silvana Savino, Mikkel Nissum, Glen Spraggon, Guido Grandi, Fabio Bagnoli and Matthew J. Bottomley..........683‑693
Published as BJ Immediate Publication 31 October 2012, doi:10.1042/BJ20121426
Abstract | Full text HTML | Full text PDF | Online Data
The dynamic action of SecA during the initiation of protein translocation
Vicki A. M. Gold, Sarah Whitehouse, Alice Robson and Ian Collinson..........695‑705
Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20121314
Abstract | Full text HTML | Full text PDF | Online Data
DNA-binding regulates site-specific ubiquitination of IRF-1
Vivien Landré, Emmanuelle Pion, Vikram Narayan, Dimitris P. Xirodimas and Kathryn L. Ball..........707‑717
Published as BJ Immediate Publication 8 November 2012, doi:10.1042/BJ20121076
Abstract | Full text HTML | Full text PDF | Online Data
Functional characterization of long-chain prenyl diphosphate synthases from tomato
Matthew O. Jones, Laura Perez‑Fons, Francesca P. Robertson, Peter M. Bramley and Paul D. Fraser..........729‑740
Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20120988
Abstract | Full text HTML | Full text PDF | Online Data
N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells
Toko Chida, Masakatsu Ando, Tasuku Matsuki, Yutaro Masu, Yuko Nagaura, Teruko Takano‑Yamamoto, Shinri Tamura and Takayasu Kobayashi..........741‑749
Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20121201
Abstract | Full text HTML | Full text PDF | Online Data
A novel transcriptional regulator, Sll1130, negatively regulates heat-responsive genes in Synechocystis sp. PCC6803
Pilla Sankara Krishna, Balaga Radha Rani, M. Karthik Mohan, Iwane Suzuki, Sisinthy Shivaji and Jogadhenu S. S. Prakash..........751‑760
Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20120928
Abstract | Full text HTML | Full text PDF | Online Data
Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation
Shailesh Kumar, Neha Kasturia, Amit Sharma, Manish Datt and Anand K. Bachhawat..........783‑794
Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20120204
Abstract | Full text HTML | Full text PDF | Online Data
Identification of a pathway by which glucose regulates β-catenin signalling via the cAMP/protein kinase A pathway in β-cell models
Emmanuelle Cognard, Coralie G. Dargaville, Deborah L. Hay and Peter R. Shepherd..........803‑811
Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20121454
Abstract | Full text HTML | Full text PDF | Online Data
Temperature-dependence of the DnaA–DNA interaction and its effect on the autoregulation of dnaA expression
Chiara Saggioro, Anne Olliver and Bianca Sclavi..........333‑341
Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20120876
Abstract | Full text HTML | Full text PDF | Online Data
An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence
Marco Guerrini, Stefano Elli, Pierre Mourier, Timothy R. Rudd, Davide Gaudesi, Benito Casu, Christian Boudier, Giangiacomo Torri and Christian Viskov..........343‑351
Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20121309
Abstract | Full text HTML | Full text PDF | Online Data
GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T-lymphocytes by promoting mitochondrial calcium accumulation
Xi Lin Chen, Daniel Serrano, Marian Mayhue, Hans‑Joachim Wieden, Jana Stankova, Guylain Boulay, Subburaj Ilangumaran and Sheela Ramanathan..........353‑364
Published as BJ Immediate Publication 26 October 2012, doi:10.1042/BJ20120516
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The transcription factor AtDOF4.2 regulates shoot branching and seed coat formation in Arabidopsis
Hong‑Feng Zou, Yu‑Qin Zhang, Wei Wei, Hao‑Wei Chen, Qing‑Xin Song, Yun‑Feng Liu, Ming‑Yu Zhao, Fang Wang, Bao‑Cai Zhang, Qing Lin, Wan‑Ke Zhang, Biao Ma, Yi‑Hua Zhou, Jin‑Song Zhang and Shou‑Yi Chen..........373‑388
Published as BJ Immediate Publication 24 October 2012, doi:10.1042/BJ20110060
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Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
Luke R. G. Pike, Dean C. Singleton, Francesca Buffa, Olga Abramczyk, Kanchan Phadwal, Ji‑Liang Li, Anna Katharina Simon, James T. Murray and Adrian L. Harris..........389‑400
Published as BJ Immediate Publication 18 October 2012, doi:10.1042/BJ20120972
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Inferring the metabolism of human orphan metabolites from their metabolic network context affirms human gluconokinase activity
Óttar Rolfsson, Giuseppe Paglia, Manuela Magnusdóttir, Bernhard Ø. Palsson and Ines Thiele..........427‑435
Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20120980
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The author has paid for access to this article to be freely available Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner
Lihua Jin, Christin L. Hanigan, Yu Wu, Wei Wang, Ben Ho Park, Patrick M. Woster and Robert A. Casero..........459‑468
Published as BJ Immediate Publication 17 October 2012, doi:10.1042/BJ20121360
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Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment
Martin Zoltner, Paul K. Fyfe, Tracy Palmer and William N. Hunter..........469‑477
Published as BJ Immediate Publication 25 October 2012, doi:10.1042/BJ20121209
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AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues
Hong Yu Wang, Serge Ducommun, Chao Quan, Bingxian Xie, Min Li, David H. Wasserman, Kei Sakamoto, Carol Mackintosh and Shuai Chen..........479‑489
Published as BJ Immediate Publication 19 October 2012, doi:10.1042/BJ20120702
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Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase
Elena M. Sánchez‑Fernández, Hanna Tarhonskaya, Khalid Al‑Qahtani, Richard J. Hopkinson, James S. O. McCullagh, Christopher J. Schofield and Emily Flashman..........491‑496
Published as BJ Immediate Publication 24 October 2012, doi:10.1042/BJ20121155
Abstract | Full text HTML | Full text PDF | Online Data
Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
Jose Félix Moruno‑Manchón, Eva Pérez‑Jiménez and Erwin Knecht..........497‑506
Published as BJ Immediate Publication 1 November 2012, doi:10.1042/BJ20121122
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Antibodies against the extracellular domain of human Notch1 receptor reveal the critical role of epidermal-growth-factor-like repeats 25–26in ligand binding and receptor activation
Ankur Sharma, Annapoorni Rangarajan and Rajan R. Dighe..........519‑530
Published as BJ Immediate Publication 17 October 2012, doi:10.1042/BJ20121153
Abstract | Full text HTML | Full text PDF | Online Data
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Katrina A. Hadfield, David I. Pattison, Bronwyn E. Brown, Liming Hou, Kerry‑Anne Rye, Michael J. Davies and Clare L. Hawkins..........531‑542
Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20121210
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hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress
Fabrizio Damiano, Alessio Rochira, Romina Tocci, Simone Alemanno, Antonio Gnoni and Luisa Siculella..........543‑553
Published as BJ Immediate Publication 30 October 2012, doi:10.1042/BJ20120906
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A versatile proline/alanine transporter in the unicellular pathogen Leishmania donovani regulates amino acid homoeostasis and osmotic stress responses
Ehud Inbar, Doreen Schlisselberg, Marianne Suter Grotemeyer, Doris Rentsch and Dan Zilberstein..........555‑566
Published as BJ Immediate Publication 21 September 2012, doi:10.1042/BJ20121262
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Activation of IP3 receptors requires an endogenous 1-8-14 calmodulin-binding motif
Yi Sun, Ana M. Rossi, Taufiq Rahman and Colin W. Taylor..........39‑49
Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20121034
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Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
Tingting Ran, Yanyan Gao, May Marsh, Wenjun Zhu, Meitian Wang, Xiang Mao, Langlai Xu, Dongqing Xu and Weiwu Wang..........51‑60
Published as BJ Immediate Publication 10 October 2012, doi:10.1042/BJ20120913
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Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics
Tommy Tillman, Mary H. Cheng, Qiang Chen, Pei Tang and Yan Xu..........61‑68
Published as BJ Immediate Publication 17 September 2012, doi:10.1042/BJ20121072
Abstract | Full text HTML | Full text PDF | Online Data
Ferroportin expression in haem oxygenase 1-deficient mice
Rafał R. Starzyński, François Canonne‑Hergaux, Małgorzata Lenartowicz, Wojciech Krzeptowski, Alexandra Willemetz, Agnieszka Styś, Joanna Bierła, Piotr Pietrzak, Tomasz Dziaman and Paweł Lipiński..........69‑78
Published as BJ Immediate Publication 20 September 2012, doi:10.1042/BJ20121139
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Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Kuan Hu, Meng Zhao, Tianlong Zhang, Manwu Zha, Chen Zhong, Yu Jiang and Jianping Ding..........79‑89
Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20120871
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Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation
Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer..........91‑99
Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20121088
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Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1
Bruno M. Fonseca, Catarina M. Paquete, Sónia E. Neto, Isabel Pacheco, Cláudio M. Soares and Ricardo O. Louro..........101‑108
Published as BJ Immediate Publication 16 October 2012, doi:10.1042/BJ20121467
Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM
Angel L. Pey, Tomas Majtan, Jose M. Sanchez‑Ruiz and Jan P. Kraus..........109‑121
Published as BJ Immediate Publication 18 September 2012, doi:10.1042/BJ20120731
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Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase
Min Tan, Bin Zhu, Ru‑Juan Liu, Xin Chen, Xiao‑Long Zhou and En‑duo Wang..........123‑131
Published as BJ Immediate Publication 4 October 2012, doi:10.1042/BJ20121258
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The author has paid for access to this article to be freely available Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5
Guillermo Senisterra, Hong Wu, Abdellah Allali‑Hassani, Gregory A. Wasney, Dalia Barsyte‑Lovejoy, Ludmila Dombrovski, Aiping Dong, Kong T. Nguyen, David Smil, Yuri Bolshan, Taraneh Hajian, Hao He, Alma Seitova, Irene Chau, Fengling Li, Gennadiy Poda, Jean‑François Couture, Peter J. Brown, Rima Al‑Awar, Matthieu Schapira, Cheryl H. Arrowsmith and Masoud Vedadi..........151‑159
Published as BJ Immediate Publication 19 September 2012, doi:10.1042/BJ20121280
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Rezymogenation of active urokinase induced by an inhibitory antibody
Longguang Jiang, Kenneth A. Botkjaer, Lisbeth M. Andersen, Cai Yuan, Peter A. Andreasen and Mingdong Huang..........161‑166
Published as BJ Immediate Publication 27 September 2012, doi:10.1042/BJ20121132
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Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum
Shaun B. Reeksting, Ingrid B. Müller, Pieter B. Burger, Emmanuel S. Burgos, Laurent Salmon, Abraham I. Louw, Lyn‑Marie Birkholtz and Carsten Wrenger..........175‑187
Published as BJ Immediate Publication 8 October 2012, doi:10.1042/BJ20120925
Abstract | Full text HTML | Full text PDF | Online Data
Haem oxygenase-1 overexpression alters intracellular iron distribution
Lilibeth Lanceta, Chi Li, Augustine M. Choi and John W. Eaton..........189‑194
Published as BJ Immediate Publication 19 September 2012, doi:10.1042/BJ20120936
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Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO cell mutant, ZPEG101
Ryuichi Natsuyama, Kanji Okumoto and Yukio Fujiki..........195‑207
Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20120911
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Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein
Søren Kløverpris, Louise L. Skov, Simon Glerup, Kasper Pihl, Michael Christiansen and Claus Oxvig..........209‑217
Published as BJ Immediate Publication 4 October 2012, doi:10.1042/BJ20120801
Abstract | Full text HTML | Full text PDF | Online Data
Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation
Mukundh N. Balasubramanian, Jixiu Shan and Michael S. Kilberg..........219‑229
Published as BJ Immediate Publication 17 September 2012, doi:10.1042/BJ20120958
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Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation Factor VII gene expression
Atsuo Suzuki, Yuhri Miyawaki, Eriko Okuyama, Moe Murata, Yumi Ando, Io Kato, Yuki Takagi, Akira Takagi, Takashi Murate, Hidehiko Saito and Tetsuhito Kojima..........231‑239
Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20121286
Abstract | Full text HTML | Full text PDF | Online Data
TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
Niall S. Kenneth, Sharon Mudie, Sanne Naron and Sonia Rocha..........275‑284
Published as BJ Immediate Publication 27 September 2012, doi:10.1042/BJ20120625
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Chitin-binding proteins of Artemia diapause cysts participate in formation of the embryonic cuticle layer of cyst shells
Wen‑Ming Ma, Hua‑Wei Li, Zhong‑Min Dai, Jin‑Shu Yang, Fan Yang and Wei‑Jun Yang..........285‑294
Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20121259
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The author has paid for access to this article to be freely available CFTR mutations altering CFTR fragmentation
Kendra Tosoni, Michelle Stobbart, Diane M. Cassidy, Andrea Venerando, Mario A. Pagano, Simão Luz, Margarida D. Amaral, Karl Kunzelmann, Lorenzo A. Pinna, Carlos M. Farinha and Anil Mehta..........295‑305
Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20121240
Abstract | Full text HTML | Full text PDF | Online Data

Volume 448

Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint)
Philippe Thebault, Dimitri Y. Chirgadze, Zhen Dou, Tom L. Blundell, Sabine Elowe and Victor M. Bolanos‑Garcia..........321‑328
Published as BJ Immediate Publication 16 October 2012, doi:10.1042/BJ20121448
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain
Jin H. Park, Yingting Liu, Mark A. Lemmon and Ravi Radhakrishnan..........417‑423
Published as BJ Immediate Publication 29 October 2012, doi:10.1042/BJ20121513
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa
Margarida Duarte and Arnaldo Videira..........297‑306
Published as BJ Immediate Publication 7 September 2012, doi:10.1042/BJ20120963
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae
Steven Haesendonckx, Vanesa Tudisca, Karin Voordeckers, Silvia Moreno, Johan M. Thevelein and Paula Portela..........307‑320
Published as BJ Immediate Publication 7 September 2012, doi:10.1042/BJ20121061
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
MpaA is a murein-tripeptide-specific zinc carboxypeptidase that functions as part of a catabolic pathway for peptidoglycan-derived peptides in γ-proteobacteria
Abbas Maqbool, Mireille Hervé, Dominique Mengin‑Lecreulx, Anthony J. Wilkinson and Gavin H. Thomas..........329‑341
Published as BJ Immediate Publication 12 September 2012, doi:10.1042/BJ20121164
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The small heat-shock protein αB-crystallin uses different mechanisms of chaperone action to prevent the amorphous versus fibrillar aggregation of α-lactalbumin
Melissa Kulig and Heath Ecroyd..........343‑352
Published as BJ Immediate Publication 24 September 2012, doi:10.1042/BJ20121187
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Controlled nuclear import of the transcription factor NTL6 reveals a cytoplasmic role of SnRK2.8 in the drought-stress response
Mi Jung Kim, Mi‑Jeong Park, Pil Joon Seo, Jin‑Su Song, Hie‑Joon Kim and Chung‑Mo Park..........353‑363
Published as BJ Immediate Publication 11 September 2012, doi:10.1042/BJ20120244
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Glucan affinity of starch synthase IIa determines binding of starch synthase I and starch-branching enzyme IIb to starch granules
Fushan Liu, Nadya Romanova, Elizabeth A. Lee, Regina Ahmed, Martin Evans, Elliot P. Gilbert, Matthew K. Morell, Michael J. Emes and Ian J. Tetlow..........373‑387
Published as BJ Immediate Publication 10 September 2012, doi:10.1042/BJ20120573
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Chun‑Hsiang Huang, Yu Sun, Tzu‑Ping Ko, Chun‑Chi Chen, Yingying Zheng, Hsiu‑Chien Chan, Xuefei Pang, Juergen Wiegel, Weilan Shao and Rey‑Ting Guo..........401‑407
Published as BJ Immediate Publication 20 September 2012, doi:10.1042/BJ20121359
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule
Dongju Jung, Lutfi Abu‑Elheiga, Rie Ayuzawa, Ziwei Gu, Takashi Shirakawa, Yukio Fujiki, Norio Nakatsuji, Salih J. Wakil and Motonari Uesugi..........409‑416
Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20121158
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and Fe–S cluster synthesis
Alok Pandey, Ramesh Golla, Heeyong Yoon, Andrew Dancis and Debkumar Pain..........171‑187
Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120951
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available 2-APB-potentiated channels amplify CatSper-induced Ca2+ signals in human sperm
Linda Lefièvre, Katherine Nash, Steven Mansell, Sarah Costello, Emma Punt, Joao Correia, Jennifer Morris, Jackson Kirkman‑Brown, Stuart M. Wilson, Christopher L. R. Barratt and Stephen Publicover..........189‑200
Published as BJ Immediate Publication 3 September 2012, doi:10.1042/BJ20120339
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
Structural insight into how Pseudomonas aeruginosa peptidoglycan-hydrolase Tse1 and its immunity protein Tsi1 function
Guijun Shang, Xiuhua Liu, Defen Lu, Junbing Zhang, Ning Li, Chunyuan Zhu, Shiheng Liu, Qian Yu, Yanyu Zhao, Heqiao Zhang, Junqiang Hu, Huaixing Cang, Sujuan Xu and Lichuan Gu..........201‑211
Published as BJ Immediate Publication 29 August 2012, doi:10.1042/BJ20120668
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The proximal C-terminus of α1C subunits is necessary for junctional membrane targeting of cardiac L-type calcium channels
Tsutomu Nakada, Bernhard E. Flucher, Toshihide Kashihara, Xiaona Sheng, Toshihide Shibazaki, Miwa Horiuchi‑Hirose, Simmon Gomi, Masamichi Hirose and Mitsuhiko Yamada..........221‑231
Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120773
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Nocturnin in the demosponge Suberites domuncula: a potential circadian clock protein controlling glycogenin synthesis in sponges
Werner E. G. Müller, Xiaohong Wang, Vlad A. Grebenjuk, Michael Korzhev, Matthias Wiens, Ute Schlossmacher and Heinz C. Schröder..........233‑242
Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120357
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Regulation of the V-type ATPase by redox modulation
Thorsten Seidel, Stefan Scholl, Melanie Krebs, Florian Rienmüller, Irene Marten, Rainer Hedrich, Miriam Hanitzsch, Patricia Janetzki, Karl‑Josef Dietz and Karin Schumacher..........243‑251
Published as BJ Immediate Publication 4 September 2012, doi:10.1042/BJ20120976
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Probing why trypanosomes assemble atypical cytochrome c with an AxxCH haem-binding motif instead of CxxCH
Michael L. Ginger, Katharine A. Sam and James W. A. Allen..........253‑260
Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120757
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Identification and characterization of a kunzeaol synthase from Thapsia garganica: implications for the biosynthesis of the pharmaceutical thapsigargin
Benjamin Pickel, Damian P. Drew, Tom Manczak, Corinna Weitzel, Henrik T. Simonsen and Dae‑Kyun Ro..........261‑271
Published as BJ Immediate Publication 31 August 2012, doi:10.1042/BJ20120654
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1
Yixing Zhou, Shilan Wu, Huanchen Wang, Yoichi Hayakawa, Gary S. Bird and Stephen B. Shears..........273‑283
Published as BJ Immediate Publication 29 August 2012, doi:10.1042/BJ20120730
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors
Ayaz Najafov, Natalia Shpiro and Dario R. Alessi..........285‑295
Published as BJ Immediate Publication 3 October 2012, doi:10.1042/BJ20121287
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon
Mark J. Coldwell, Ulrike Sack, Joanne L. Cowan, Rachel M. Barrett, Markete Vlasak, Keiley Sivakumaran and Simon J. Morley..........1‑11
Published as BJ Immediate Publication 21 August 2012, doi:10.1042/BJ20111765
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
DNA-dependent Oct4–Sox2 interaction and diffusion properties characteristic of the pluripotent cell state revealed by fluorescence spectroscopy
Chen Sok Lam, Tapan Kumar Mistri, Yong Hwee Foo, Thankiah Sudhaharan, Hui Theng Gan, David Rodda, Leng Hiong Lim, Chai Chou, Paul Robson, Thorsten Wohland and Sohail Ahmed..........21‑33
Published as BJ Immediate Publication 22 August 2012, doi:10.1042/BJ20120725
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions
Heather J. Spence, Paul Timpson, Hao Ran Tang, Robert H. Insall and Laura M. Machesky..........35‑42
Published as BJ Immediate Publication 21 August 2012, doi:10.1042/BJ20112206
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes
Yeliz Angin, Laura K. M. Steinbusch, Peter J. Simons, Sabrina Greulich, Nicole T. H. Hoebers, Kim Douma, Marc A. M. J. van Zandvoort, Will A. Coumans, Wino Wijnen, Michaela Diamant, D. Margriet Ouwens, Jan F. C. Glatz and Joost J. F. P. Luiken..........43‑53
Published as BJ Immediate Publication 10 July 2012, doi:10.1042/BJ20120060
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
Jonas Boehringer, Christiane Riedinger, Konstantinos Paraskevopoulos, Eachan O. D. Johnson, Edward D. Lowe, Christina Khoudian, Dominique Smith, Martin E. M. Noble, Colin Gordon and Jane A. Endicott..........55‑65
Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20120542
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase
Hugh P. Morgan, Martin J. Walsh, Elizabeth A. Blackburn, Martin A. Wear, Matthew B. Boxer, Min Shen, Henrike Veith, Iain W. McNae, Matthew W. Nowicki, Paul A. M. Michels, Douglas S. Auld, Linda A. Fothergill‑Gilmore and Malcolm D. Walkinshaw..........67‑72
Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20121014
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer Methylene Blue
Mathilde M. Triquigneaux, Marilyn Ehrenshaft, Esther Roth, Israel Silman, Yakov Ashani, Ronald P. Mason, Lev Weiner and Leesa J. Deterding..........83‑91
Published as BJ Immediate Publication 13 August 2012, doi:10.1042/BJ20120992
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels
Nicole Zimmermann, Jürgen Zschocke, Tatjana Perisic, Shuang Yu, Florian Holsboer and Theo Rein..........93‑102
Published as BJ Immediate Publication 13 August 2012, doi:10.1042/BJ20120674
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer
Mayilaadumveettil Nishana and Sathees C. Raghavan..........115‑125
Published as BJ Immediate Publication 15 August 2012, doi:10.1042/BJ20121031
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
BIK (NBK) is a mediator of the sensitivity of Fanconi anaemia group C lymphoblastoid cell lines to interstrand DNA cross-linking agents
Inés Prieto‑Remón, Dámaso Sánchez‑Carrera, Mónica López‑Duarte, Carlos Richard and Carlos Pipaón..........153‑163
Published as BJ Immediate Publication 8 August 2012, doi:10.1042/BJ20120327
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 447

Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart
Choon Kee Min, Dong Rim Yeom, Kyung‑Eun Lee, Hye‑Kyeong Kwon, Moonkyung Kang, Yeon‑Soo Kim, Zee Yong Park, Hyesung Jeon and Do Han Kim..........371‑379
Published as BJ Immediate Publication 7 August 2012, doi:10.1042/BJ20120705
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Functional comparison of Deinococcus radiodurans Dps proteins suggests distinct in vivo roles
Brian J. Reon, Khoa H. Nguyen, Gargi Bhattacharyya and Anne Grove..........381‑391
Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20120902
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source
Jia X. Shen, Sebastian Wachten, Michelle L. Halls, Katy L. Everett and Dermot M. F. Cooper..........393‑405
Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20120279
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation
Jia Hu, Zhong Chen, Ding Xia, Jia Wu, Hua Xu and Zhang‑Qun Ye..........407‑416
Published as BJ Immediate Publication 5 October 2012, doi:10.1042/BJ20120256
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells
Dhara N. Amin, Natalia Sergina, Lionel Lim, Andrei Goga and Mark M. Moasser..........417‑425
Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20120724
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of ML-IAP protein stability and physiological role in vivo
Eugene Varfolomeev, Elham Moradi, Jasmin N. Dynek, Jiping Zha, Anna V. Fedorova, Kurt Deshayes, Wayne J. Fairbrother, Kim Newton, Jennifer Le Couter and Domagoj Vucic..........427‑436
Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20121103
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Regulation of hepatic insulin sensitivity by activating signal co-integrator-2
Geun Hyang Kim, Kyung Jin Lee, Gyun‑Sik Oh, Jin Yoon, Hae Won Kim and Seung‑Whan Kim..........437‑447
Published as BJ Immediate Publication 6 August 2012, doi:10.1042/BJ20120861
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumour cells
Takanobu Tagawa, Takeshi Haraguchi, Hiroaki Hiramatsu, Kazuyoshi Kobayashi, Kouhei Sakurai, Ken‑Ichi Inada and Hideo Iba..........449‑455
Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120434
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Protein kinase Cϵ activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection
Odile Dumont, Hayley Mylroie, Andrea Bauer, Damien Calay, Andrea Sperone, Clare Thornton, Shahir S. Hamdulay, Nadira Ali, Joseph J. Boyle, Joan R. Choo, Allen M. Samarel, Dorian O. Haskard, Anna M. Randi, Paul C. Evans and Justin C. Mason..........193‑204
Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120574
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications
Michaela Blech, Daniel Seeliger, Barbara Kistler, Margit M. T. Bauer, Mathias Hafner, Stefan Hörer, Markus Zeeb, Herbert Nar and John E. Park..........205‑215
Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120884
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Mapping the N-glycome of human von Willebrand factor
Kevin Canis, Thomas A. J. McKinnon, Agata Nowak, Stuart M. Haslam, Maria Panico, Howard R. Morris, Mike A. Laffan and Anne Dell..........217‑228
Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120810
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Dedifferentiated follicular granulosa cells derived from pig ovary can transdifferentiate into osteoblasts
Yoshinao Oki, Hiromasa Ono, Takeharu Motohashi, Nobuki Sugiura, Hiroyuki Nobusue and Koichiro Kano..........239‑248
Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120172
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Nitric oxide inhibits the ATPase activity of the chaperone-like AAA+ ATPase CDC48, a target for S-nitrosylation in cryptogein signalling in tobacco cells
Jéremy Astier, Angélique Besson‑Bard, Olivier Lamotte, Jean Bertoldo, Stéphane Bourque, Hernán Terenzi and David Wendehenne..........249‑260
Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120257
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection
Qiang Zhang, Junbing Wu, Rong Wu, Jun Ma, Guiping Du, Renjie Jiao, Yong Tian, Zheng Zheng and Zengqiang Yuan..........261‑269
Published as BJ Immediate Publication 8 August 2012, doi:10.1042/BJ20120598
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
In vitro reconstitution of RNA primer removal in Archaea reveals the existence of two pathways
Ghislaine Henneke..........271‑280
Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120959
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
Masato Ogura, Junko Yamaki, Miwako K. Homma and Yoshimi Homma..........281‑289
Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20120509
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of Arabidopsis calcium-dependent protein kinases: activated or not by calcium?
Marie Boudsocq, Marie‑Jo Droillard, Leslie Regad and Christiane Laurière..........291‑299
Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20112072
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes
Ivana Campia, Valentina Sala, Joanna Kopecka, Christian Leo, Nico Mitro, Costanzo Costamagna, Donatella Caruso, Gianpiero Pescarmona, Tiziana Crepaldi, Dario Ghigo, Amalia Bosia and Chiara Riganti..........301‑311
Published as BJ Immediate Publication 30 July 2012, doi:10.1042/BJ20120200
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells
Shin‑Ae Kang, Hyun‑Soo Cho, Jong Bok Yoon, In Kwon Chung and Seung‑Taek Lee..........313‑320
Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120803
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Selective activation of Toll-like receptor 7 in activated hepatic stellate cells may modulate their profibrogenic phenotype
Ming‑Huei Chou, Ying‑Hsien Huang, Tsun‑Mei Lin, Yung‑Ying Du, Po‑Chin Tsai, Chih‑Sung Hsieh and Jiin‑Haur Chuang..........25‑34
Published as BJ Immediate Publication 5 July 2012, doi:10.1042/BJ20112058
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structural origin of polymorphism of Alzheimer's amyloid β-fibrils
Audrey Agopian and Zhefeng Guo..........43‑50
Published as BJ Immediate Publication 23 July 2012, doi:10.1042/BJ20120034
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt
Maaike Kockx, Donna L. Dinnes, Kuan‑Yen Huang, Laura J. Sharpe, Wendy Jessup, Andrew J. Brown and Leonard Kritharides..........51‑60
Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20111891
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important for cell adhesion
Vinita Wadhawan, Yogesh A. Kolhe, Nikhil Sangith, Amit Kumar Singh Gautam and Prasanna Venkatraman..........61‑70
Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20111432
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion
Sarwat Naz, Prathibha Ranganathan, Priyanka Bodapati, Arun H. Shastry, Laxmi N. Mishra and Paturu Kondaiah..........81‑91
Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20120014
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression
Ming Ji, Shuping Yang, Yuanhong Chen, Ling Xiao, Lin Zhang and Jixin Dong..........93‑102
Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20120751
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A novel pathway of ceramide metabolism in Saccharomyces cerevisiae
Natalia S. Voynova, Christine Vionnet, Christer S. Ejsing and Andreas Conzelmann..........103‑114
Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120712
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
PDIp is a major intracellular oestrogen-storage protein that modulates tissue levels of oestrogen in the pancreas
Xinmiao Fu, Pan Wang, Masayuki Fukui, Cheng Long, Linxiang Yin, Hye Joung Choi and Bao Ting Zhu..........115‑123
Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20120868
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes
Ivan H. W. Ng, Dominic C. H. Ng, David A. Jans and Marie A. Bogoyevitch..........125‑136
Published as BJ Immediate Publication 17 July 2012, doi:10.1042/BJ20120941
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle
Yu‑Chiang Lai, Yang Liu, Roxane Jacobs and Mark H. Rider..........137‑147
Published as BJ Immediate Publication 13 July 2012, doi:10.1042/BJ20120772
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation
Madhurima Saha, Audrey Carriere, Mujeeburahiman Cheerathodi, Xiaocui Zhang, Geneviève Lavoie, John Rush, Philippe P. Roux and Bryan A. Ballif..........159‑166
Published as BJ Immediate Publication 25 July 2012, doi:10.1042/BJ20120938
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase
Xiaoxiao Peng, Jianqiang Xu and Elias S. J. Arnér..........167‑174
Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20120683
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 446

The biological roles of glutaredoxins
Elke Ströher and A. Harvey Millar..........333‑348
Published on the Internet 28 August 2012, doi:10.1042/BJ20112131
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
In vivo phosphorylation of FtsZ2 in Arabidopsis thaliana
Daniela Gargano, Jodi Maple‑Grødem and Simon G. Møller..........517‑521
Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20120404
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors
Xiaozhong Shi, David C. Seldin and Daniel J. Garry..........349‑357
Published as BJ Immediate Publication 20 June 2012, doi:10.1042/BJ20120563
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient
Jung‑Il Chae, Dong‑Wook Kim, Nayeon Lee, Young‑Joo Jeon, Iksoo Jeon, Jihye Kwon, Jumi Kim, Yunjo Soh, Dong‑Seok Lee, Kang Seok Seo, Nag‑Jin Choi, Byoung Chul Park, Sung Hyun Kang, Joohyun Ryu, Seung‑Hun Oh, Dong Ah Shin, Dong Ryul Lee, Jeong Tae Do, In‑Hyun Park, George Q. Daley and Jihwan Song..........359‑371
Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20111495
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The author has paid for access to this article to be freely available Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents
Philip M. Kubara, Sophie Kernéis‑Golsteyn, Aurélie Studény, Brittany B. Lanser, Laurent Meijer and Roy M. Golsteyn..........373‑381
Published as BJ Immediate Publication 11 June 2012, doi:10.1042/BJ20120385
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells
Kyubo Kim, Youlia M. Petrova, Brenton L. Scott, Rupesh Nigam, Anurag Agrawal, Christopher M. Evans, Zoulikha Azzegagh, Alejandra Gomez, Elsa M. Rodarte, Vesa M. Olkkonen, Rustam Bagirzadeh, Lucia Piccotti, Binhui Ren, Joo‑Heon Yoon, James A. McNew, Roberto Adachi, Michael J. Tuvim and Burton F. Dickey..........383‑394
Published as BJ Immediate Publication 14 June 2012, doi:10.1042/BJ20120057
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Crystal structure of the dopamine N-acetyltransferase–acetyl-CoA complex provides insights into the catalytic mechanism
Kuo‑Chang Cheng, Jhen‑Ni Liao and Ping‑Chiang Lyu..........395‑404
Published as BJ Immediate Publication 21 June 2012, doi:10.1042/BJ20120520
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode
Nicholas A. Larsen, Tory J. Nash, Marshall Morningstar, Adam B. Shapiro, Camil Joubran, Carolyn J. Blackett, Arthur D. Patten, P. Ann Boriack‑Sjodin and Peter Doig..........405‑413
Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20120596
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells
Guohui Wang, Xuebao Zhang, Jin‑Sook Lee, Xiaogang Wang, Zeng‑Quan Yang and Kezhong Zhang..........415‑425
Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20112050
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na+/H+ exchanger isoform 1)
Wataru Nunomura, Sheryl P. Denker, Diane L. Barber, Yuichi Takakuwa and Philippe Gascard..........427‑435
Published as BJ Immediate Publication 25 June 2012, doi:10.1042/BJ20120535
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase
Swati Chauhan, Filip Jelen, Iraida Sharina and Emil Martin..........445‑453
Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20111882
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction
Paul M. Titchenell, Cheng‑Mao Lin, Jason M. Keil, Jeffrey M. Sundstrom, Charles D. Smith and David A. Antonetti..........455‑467
Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20111961
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Dimerization is necessary for MIM-mediated membrane deformation and endocytosis
Meng Cao, Tailan Zhan, Min Ji and Xi Zhan..........469‑475
Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20120329
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Low temperature highlights the functional role of the cell wall integrity pathway in the regulation of growth in Saccharomyces cerevisiae
Isaac Córcoles‑Sáez, Lídia Ballester‑Tomas, Maria A. de la Torre‑Ruiz, Jose A. Prieto and Francisca Randez‑Gil..........477‑488
Published as BJ Immediate Publication 29 June 2012, doi:10.1042/BJ20120634
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Effect of homomeric P450–P450 complexes on P450 function
James R. Reed, J. Patrick Connick, Dongmei Cheng, George F. Cawley and Wayne L. Backes..........489‑497
Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120636
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity
Ryan Stapley, Benjamin Y. Owusu, Angela Brandon, Marianne Cusick, Cilina Rodriguez, Marisa B. Marques, Jeffrey D. Kerby, Scott R. Barnum, Jordan A. Weinberg, Jack R. Lancaster and Rakesh P. Patel..........499‑508
Published as BJ Immediate Publication 21 June 2012, doi:10.1042/BJ20120675
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
USP18 establishes the transcriptional and anti-proliferative interferon α/β differential
Véronique Francois‑Newton, Mark Livingstone, Béatrice Payelle‑Brogard, Gilles Uzé and Sandra Pellegrini..........509‑516
Published as BJ Immediate Publication 26 June 2012, doi:10.1042/BJ20120541
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity
I. J. Frame, Emilio F. Merino, Vern L. Schramm, María B. Cassera and Myles H. Akabas..........179‑190
Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20112220
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products
James R. Krycer, Lisa Phan and Andrew J. Brown..........191‑201
Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20120545
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Transcriptional networks driving enhancer function in the CFTR gene
Jenny L. Kerschner and Ann Harris..........203‑212
Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120693
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
MMP proteolysis of the human extracellular matrix protein aggrecan is mainly a process of normal turnover
André Struglics and Maria Hansson..........213‑223
Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120274
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Acidic stress induces the formation of P-bodies, but not stress granules, with mild attenuation of bulk translation in Saccharomyces cerevisiae
Aya Iwaki and Shingo Izawa..........225‑233
Published as BJ Immediate Publication 12 June 2012, doi:10.1042/BJ20120583
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism
Ivana Biljan, Gabriele Giachin, Gregor Ilc, Igor Zhukov, Janez Plavec and Giuseppe Legname..........243‑251
Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20111940
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster
Qian Han, Howard Robinson and Jianyong Li..........253‑260
Published as BJ Immediate Publication 12 June 2012, doi:10.1042/BJ20120416
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended
Salla Ruskamo, Robert Gilbert, Gregor Hofmann, Pengju Jiang, Iain D. Campbell, Jari Ylänne and Ulla Pentikäinen..........261‑269
Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20120361
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates
Carolin Sörensson, Marit Lenman, Jenny Veide‑Vilg, Simone Schopper, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás, Scott C. Peck and Erik Andreasson..........271‑278
Published as BJ Immediate Publication 25 May 2012, doi:10.1042/BJ20111809
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
Systematic interaction analysis of human lipocalin-type prostaglandin D synthase with small lipophilic ligands
Satoshi Kume, Young‑Ho Lee, Yuya Miyamoto, Harumi Fukada, Yuji Goto and Takashi Inui..........279‑289
Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20120324
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Interaction specificity between the chaperone and proteolytic components of the cyanobacterial Clp protease
Anders Tryggvesson, Frida M. Ståhlberg, Axel Mogk, Kornelius Zeth and Adrian K. Clarke..........311‑320
Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20120649
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Homodimerization and isoform-specific heterodimerization of neuroligins
Alexandros Poulopoulos, Tolga Soykan, Liam P. Tuffy, Matthieu Hammer, Frédérique Varoqueaux and Nils Brose..........321‑330
Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120808
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A novel role for the transcription factor HIF-1α in the formation of mast cell extracellular traps
Katja Branitzki‑Heinemann, Cheryl Y. Okumura, Lena Völlger, Yuko Kawakami, Toshiaki Kawakami, Hassan Y. Naim, Victor Nizet and Maren Von Köckritz‑Blickwede..........159‑163
Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120658
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells
Alasdair I. MacDonald, Peng Sun, Hegel Hernandez‑Lopez, Trond Aasen, Malcolm B. Hodgins, Michael Edward, Sally Roberts, Paola Massimi, Miranda Thomas, Lawrence Banks and Sheila V. Graham..........9‑21
Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20111144
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Myostatin is a novel tumoral factor that induces cancer cachexia
Sudarsanareddy Lokireddy, Isuru Wijerupage Wijesoma, Sabeera Bonala, Meng Wei, Siu Kwan Sze, Craig McFarlane, Ravi Kambadur and Mridula Sharma..........23‑36
Published as BJ Immediate Publication 23 May 2012, doi:10.1042/BJ20112024
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus
Sujit Dutta, Garvita Gupta, Yook‑Wah Choi, Masayo Kotaka, Burtram C. Fielding, Jianxing Song and Yee‑Joo Tan..........37‑46
Published as BJ Immediate Publication 28 May 2012, doi:10.1042/BJ20120001
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice
Ozlem Guzeloglu‑Kayisli, Maria D. Lalioti, Fulya Aydiner, Isaac Sasson, Orkan Ilbay, Denny Sakkas, Katie M. Lowther, Lisa M. Mehlmann and Emre Seli..........47‑58
Published as BJ Immediate Publication 24 May 2012, doi:10.1042/BJ20120467
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Redox properties of the disulfide bond of human Cu,Zn superoxide dismutase and the effects of human glutaredoxin 1
Samantha D. Bouldin, Maxwell A. Darch, P. John Hart and Caryn E. Outten..........59‑67
Published as BJ Immediate Publication 31 May 2012, doi:10.1042/BJ20120075
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells
Shanshan Wang, Zhao Wang, Shengchen Lin, Weili Zheng, Rui Wang, Shikai Jin, Jinan Chen, Lihua Jin and Yong Li..........79‑87
Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20120726
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif
Bohao Chen, Rona Hsu, Zhenping Li, Paul C. Kogut, Qingxia Du, Kelly Rouser, Blanca Camoretti‑Mercado and Julian Solway..........89‑98
Published as BJ Immediate Publication 25 May 2012, doi:10.1042/BJ20111942
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
Iakov N. Rudenko, Alice Kaganovich, David N. Hauser, Aleksandra Beylina, Ruth Chia, Jinhui Ding, Dragan Maric, Howard Jaffe and Mark R. Cookson..........99‑111
Published as BJ Immediate Publication 22 May 2012, doi:10.1042/BJ20120637
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Desulfovibrio vulgaris bacterioferritin uses H2O2 as a co-substrate for iron oxidation and reveals DPS-like DNA protection and binding activities
Cristina G. Timóteo, Márcia Guilherme, Daniela Penas, Filipe Folgosa, Pedro Tavares and Alice S. Pereira..........125‑133
Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20111439
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1
Stephen J. Fairweather, Angelika Bröer, Megan L. O'Mara and Stefan Bröer..........135‑148
Published as BJ Immediate Publication 7 June 2012, doi:10.1042/BJ20120307
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 445

A key structural domain of the Candida albicans Mdr1 protein
Ajeet Mandal, Antresh Kumar, Ashutosh Singh, Andrew M. Lynn, Khyati Kapoor and Rajendra Prasad..........313‑322
Published as BJ Immediate Publication 16 May 2012, doi:10.1042/BJ20120190
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
p130Cas-dependent actin remodelling regulates myogenic differentiation
Keiko Kawauchi, Wee Wee Tan, Keigo Araki, Farhana Binte Abu Bakar, Minsoo Kim, Hideaki Fujita, Hiroaki Hirata and Yasuhiro Sawada..........323‑332
Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20112169
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Glutathionylation of cytosolic glyceraldehyde-3-phosphate dehydrogenase from the model plant Arabidopsis thaliana is reversed by both glutaredoxins and thioredoxins in vitro
Mariette Bedhomme, Mattia Adamo, Christophe H. Marchand, Jérémy Couturier, Nicolas Rouhier, Stéphane D. Lemaire, Mirko Zaffagnini and Paolo Trost..........337‑347
Published as BJ Immediate Publication 21 May 2012, doi:10.1042/BJ20120505
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Solution structure of the core SMN–Gemin2 complex
Kathryn L. Sarachan, Kathleen G. Valentine, Kushol Gupta, Veronica R. Moorman, John M. Gledhill, Matthew Bernens, Cecilia Tommos, A. Joshua Wand and Gregory D. Van Duyne..........361‑370
Published as BJ Immediate Publication 21 May 2012, doi:10.1042/BJ20120241
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2
Haiyan Sun, Choon‑myung Lee, Shweta Tripathi, Kyung‑Bo Kim and Edward T. Morgan..........377‑382
Published as BJ Immediate Publication 22 May 2012, doi:10.1042/BJ20120820
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Recruitment and membrane interactions of host cell proteins during attachment of enteropathogenic and enterohaemorrhagic Escherichia coli
Diana Munera, Eric Martinez, Svetlana Varyukhina, Arvind Mahajan, Jesus Ayala‑Sanmartin and Gad Frankel..........383‑392
Published as BJ Immediate Publication 16 May 2012, doi:10.1042/BJ20120533
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor
Young‑Woong Kim, Jinah Park, Hyun‑Ju Lee, So‑Young Lee and Seong‑Jin Kim..........403‑411
Published as BJ Immediate Publication 10 May 2012, doi:10.1042/BJ20111923
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways
Dieter R. Samyn, Lorena Ruiz‑Pávon, Michael R. Andersson, Yulia Popova, Johan M. Thevelein and Bengt L. Persson..........413‑422
Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20112086
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism
Ryuta Tobe, Min‑Hyuk Yoo, Noelia Fradejas, Bradley A. Carlson, Soledad Calvo, Vadim N. Gladyshev and Dolph L. Hatfield..........423‑430
Published as BJ Immediate Publication 17 May 2012, doi:10.1042/BJ20120618
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The MEKK1 SWIM domain is a novel substrate receptor for c-Jun ubiquitylation
Michael A. Rieger, Tyler Duellman, Christopher Hooper, Magdalene Ameka, Joanna C. Bakowska and Bruce D. Cuevas..........431‑439
Published as BJ Immediate Publication 14 May 2012, doi:10.1042/BJ20120406
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A key role for Mg2+ in TRPM7's control of ROS levels during cell stress
Hsiang‑Chin Chen, Li‑Ting Su, Omayra González‑Pagán, Jeffrey D. Overton and Loren W. Runnels..........441‑448
Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20120248
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A urea channel from Bacillus cereus reveals a novel hexameric structure
Gerard H. M. Huysmans, Nathan Chan, Jocelyn M. Baldwin, Vincent L. G. Postis, Svetomir B. Tzokov, Sarah E. Deacon, Sylvia Y. M. Yao, James D. Young, Michael J. McPherson, Per A. Bullough and Stephen A. Baldwin..........157‑166
Published as BJ Immediate Publication 3 May 2012, doi:10.1042/BJ20120169
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes
Benjamin W. Cook and Gary S. Shaw..........167‑174
Published as BJ Immediate Publication 8 May 2012, doi:10.1042/BJ20120504
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The crystal structure of human α1-microglobulin reveals a potential haem-binding site
Winfried Meining and Arne Skerra..........175‑182
Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20120448
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica
Sofia Lemak, Anatoli Tchigvintsev, Pierre Petit, Robert Flick, Alexander U. Singer, Greg Brown, Elena Evdokimova, Olga Egorova, Claudio F. Gonzalez, Tatyana N. Chernikova, Michail M. Yakimov, Michael Kube, Richard Reinhardt, Peter N. Golyshin, Alexei Savchenko and Alexander F. Yakunin..........193‑203
Published as BJ Immediate Publication 23 April 2012, doi:10.1042/BJ20112113
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The saposin-like protein SPP-12 is an antimicrobial polypeptide in the pharyngeal neurons of Caenorhabditis elegans and participates in defence against a natural bacterial pathogen
Aylin Hoeckendorf, Mareike Stanisak and Matthias Leippe..........205‑212
Published as BJ Immediate Publication 23 April 2012, doi:10.1042/BJ20112102
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase
Oscar H. Martínez‑Costa, Valentina Sánchez, Antonio Lázaro, Eloy D. Hernández, Keith Tornheim and Juan J. Aragón..........213‑218
Published as BJ Immediate Publication 25 April 2012, doi:10.1042/BJ20120173
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila
Xavier Kubiak, Delphine Dervins‑Ravault, Benjamin Pluvinage, Alain F. Chaffotte, Laura Gomez‑Valero, Julien Dairou, Florent Busi, Jean‑Marie Dupret, Carmen Buchrieser and Fernando Rodrigues‑Lima..........219‑228
Published as BJ Immediate Publication 30 April 2012, doi:10.1042/BJ20120528
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Different molecular bases underlie the mitochondrial respiratory activity in the homoeothermic spadices of Symplocarpus renifolius and the transiently thermogenic appendices of Arum maculatum
Yusuke Kakizaki, Anthony L. Moore and Kikukatsu Ito..........237‑246
Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20111978
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity
Norma Frizzell, Sonia A. Thomas, James A. Carson and John W. Baynes..........247‑254
Published as BJ Immediate Publication 24 April 2012, doi:10.1042/BJ20112142
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1)
Qiong Lin, Jian Wang, Chandra Childress and Wannian Yang..........255‑264
Published as BJ Immediate Publication 3 May 2012, doi:10.1042/BJ20111575
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models
Nancy Zaarour, Marion Berenguer, Yannick Le Marchand‑Brustel and Roland Govers..........265‑273
Published as BJ Immediate Publication 30 April 2012, doi:10.1042/BJ20120232
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana
Hannah Birke, Florian H. Haas, Luit J. De Kok, Janneke Balk, Markus Wirtz and Rüdiger Hell..........275‑283
Published as BJ Immediate Publication 2 May 2012, doi:10.1042/BJ20120038
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The human NUPR1/P8 gene is transcriptionally activated by transforming growth factor β via the SMAD signalling pathway
Roxane M. Pommier, Johann Gout, David F. Vincent, Carla E. Cano, Bastien Kaniewski, Sylvie Martel, Jonathan Rodriguez, Geneviève Fourel, Ulrich Valcourt, Julien C. Marie, Juan L. Iovanna and Laurent Bartholin..........285‑293
Published as BJ Immediate Publication 27 June 2012, doi:10.1042/BJ20120368
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Multidimensional epistasis and fitness landscapes in enzyme evolution
Wei Zhang, Daniel F. A. R. Dourado, Pedro Alexandrino Fernandes, Maria João Ramos and Bengt Mannervik..........39‑46
Published as BJ Immediate Publication 26 April 2012, doi:10.1042/BJ20120136
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor
Ilaria Lamberto, Haina Qin, Roberta Noberini, Lakshmanane Premkumar, Caroline Bourgin, Stefan J. Riedl, Jianxing Song and Elena B. Pasquale..........47‑56
Published as BJ Immediate Publication 10 April 2012, doi:10.1042/BJ20120408
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Neisseria meningitidis and Neisseria gonorrhoeae are differently adapted in the regulation of denitrification: single nucleotide polymorphisms that enable species-specific tuning of the aerobic–anaerobic switch
James Edwards, Diana Quinn, Karyn‑Anne Rowbottom, Jean L. Whittingham, Melanie J. Thomson and James W. B. Moir..........69‑79
Published as BJ Immediate Publication 18 April 2012, doi:10.1042/BJ20111984
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel
Meenu N. Perera, Shang H. Lin, Yuri K. Peterson, Alicja Bielawska, Zdzislaw M. Szulc, Robert Bittman and Marco Colombini..........81‑91
Published as BJ Immediate Publication 11 April 2012, doi:10.1042/BJ20112103
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation
Kyle Friend, Matthew Brook, F. Betül Bezirci, Michael D. Sheets, Nicola K. Gray and Emre Seli..........93‑100
Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20120304
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A conserved cysteine residue is involved in disulfide bond formation between plant plasma membrane aquaporin monomers
Gerd P. Bienert, Damien Cavez, Arnaud Besserer, Marie C. Berny, Dimitri Gilis, Marianne Rooman and François Chaumont..........101‑111
Published as BJ Immediate Publication 17 April 2012, doi:10.1042/BJ20111704
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues
Johan Vande Voorde, Federico Gago, Kristof Vrancken, Sandra Liekens and Jan Balzarini..........113‑123
Published as BJ Immediate Publication 4 April 2012, doi:10.1042/BJ20112225
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
β2-Glycoprotein I inhibits endothelial cell migration through the nuclear factor κB signalling pathway and endothelial nitric oxide synthase activation
Wen‑Chin Chiu, Tzeon‑Jye Chiou and An‑Na Chiang..........125‑133
Published as BJ Immediate Publication 10 April 2012, doi:10.1042/BJ20111383
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
Kosuke Yamamoto, Ahmad Trad, Anja Baumgart, Linda Hüske, Inken Lorenzen, Athena Chalaris, Joachim Grötzinger, Tobias Dechow, Jürgen Scheller and Stefan Rose‑John..........135‑144
Published as BJ Immediate Publication 17 April 2012, doi:10.1042/BJ20120433
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 444

EHD2 shuttles to the nucleus and represses transcription
Olga Pekar, Sigi Benjamin, Hilla Weidberg, Silvia Smaldone, Francesco Ramirez and Mia Horowitz..........383‑394
Published as BJ Immediate Publication 26 March 2012, doi:10.1042/BJ20111268
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors
Ditte H. Welner, Søren Lindemose, J. Günter Grossmann, Niels Erik Møllegaard, Addie N. Olsen, Charlotte Helgstrand, Karen Skriver and Leila Lo Leggio..........395‑404
Published as BJ Immediate Publication 29 March 2012, doi:10.1042/BJ20111742
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif
Ivo C. Martins, Francisco Gomes‑Neto, André F. Faustino, Filomena A. Carvalho, Fabiana A. Carneiro, Patricia T. Bozza, Ronaldo Mohana‑Borges, Miguel A. R. B. Castanho, Fábio C. L. Almeida, Nuno C. Santos and Andrea T. Da Poian..........405‑415
Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112219
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Bivalent and co-operative binding of complement Factor H to heparan sulfate and heparin
Sanaullah Khan, Ruodan Nan, Jayesh Gor, Barbara Mulloy and Stephen J. Perkins..........417‑428
Published as BJ Immediate Publication 3 April 2012, doi:10.1042/BJ20120183
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors
Akila Jayaraman, Xiaoying Koh, Jing Li, Rahul Raman, Karthik Viswanathan, Zachary Shriver and Ram Sasisekharan..........429‑435
Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20112101
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A glycosynthase derived from an inverting GH19 chitinase from the moss Bryum coronatum
Takayuki Ohnuma, Tatsuya Fukuda, Satoshi Dozen, Yuji Honda, Motomitsu Kitaoka and Tamo Fukamizo..........437‑443
Published as BJ Immediate Publication 21 March 2012, doi:10.1042/BJ20120036
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801
Claudio F. Gonzalez, Anatoli Tchigvintsev, Greg Brown, Robert Flick, Elena Evdokimova, Xiaohui Xu, Jerzy Osipiuk, Marianne E. Cuff, Susan Lynch, Andrzej Joachimiak, Alexei Savchenko and Alexander F. Yakunin..........445‑455
Published as BJ Immediate Publication 23 March 2012, doi:10.1042/BJ20112032
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A functional description of CymA, an electron-transfer hub supporting anaerobic respiratory flexibility in Shewanella
Sophie J. Marritt, Thomas G. Lowe, Jordan Bye, Duncan G. G. McMillan, Liang Shi, Jim Fredrickson, John Zachara, David J. Richardson, Myles R. Cheesman, Lars J. C. Jeuken and Julea N. Butt..........465‑474
Published as BJ Immediate Publication 29 March 2012, doi:10.1042/BJ20120197
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic Ca2+ homoeostasis
Linghuo Jiang, Joerg Alber, Jihong Wang, Wei Du, Xuexue Yang, Xichuan Li, Dominique Sanglard and Joachim Geyer..........497‑502
Published as BJ Immediate Publication 24 April 2012, doi:10.1042/BJ20112166
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase
Charles O. Brown, Kelley Salem, Brett A. Wagner, Soumen Bera, Neeraj Singh, Ajit Tiwari, Amit Choudhury, Garry R. Buettner and Apollina Goel..........515‑527
Published as BJ Immediate Publication 3 April 2012, doi:10.1042/BJ20112019
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis
Zhaohua Zheng, Syazwani I. Amran, Jiuxiang Zhu, Oleg Schmidt‑Kittler, Kenneth W. Kinzler, Bert Vogelstein, Peter R. Shepherd, Philip E. Thompson and Ian G. Jennings..........529‑535
Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20120499
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics
Itzhak Nissim, Oksana Horyn, Ilana Nissim, Yevgeny Daikhin, Suzanne L. Wehrli, Marc Yudkoff and Franz M. Matschinsky..........537‑551
Published as BJ Immediate Publication 26 March 2012, doi:10.1042/BJ20120163
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition
Anne R. Diers, Katarzyna A. Broniowska, Ching‑Fang Chang and Neil Hogg..........561‑571
Published as BJ Immediate Publication 30 March 2012, doi:10.1042/BJ20120294
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity
Mitchell E. Menezes, Aparna Mitra, Lalita A. Shevde and Rajeev S. Samant..........573‑580
Published as BJ Immediate Publication 28 March 2012, doi:10.1042/BJ20120205
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP
Xue‑Yuan Dong, Xiaoying Fu, Songqing Fan, Peng Guo, Dan Su and Jin‑Tang Dong..........581‑590
Published as BJ Immediate Publication 28 March 2012, doi:10.1042/BJ20111890
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Neuronal caspase 2 activity and function requires RAIDD, but not PIDD
Elena M. Ribe, Ying Y. Jean, Rebecca L. Goldstein, Claudia Manzl, Leonidas Stefanis, Andreas Villunger and Carol M. Troy..........591‑599
Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20111588
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Synthesis of inositol phosphate ligands of plant hormone–receptor complexes: pathways of inositol hexakisphosphate turnover
David E. Hanke, Paroo N. Parmar, Samuel E. K. Caddick, Porntip Green and Charles A. Brearley..........601‑609
Published as BJ Immediate Publication 20 March 2012, doi:10.1042/BJ20111811
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate
Marcella Ma, Heather P. Harding, Stephen O'Rahilly, David Ron and Giles S. H. Yeo..........183‑187
Published as BJ Immediate Publication 21 March 2012, doi:10.1042/BJ20120065
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Construction of histidine-tagged yeast mitochondrial cytochrome c oxidase for facile purification of mutant forms
Brigitte Meunier, Amandine Maréchal and Peter R. Rich..........199‑204
Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20120116
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells1
Gaspar E. Cánepa, Maria Sol Degese, Alexandre Budu, Celia R. S. Garcia and Carlos A. Buscaglia..........211‑218
Published as BJ Immediate Publication 20 March 2012, doi:10.1042/BJ20120074
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of a novel copper-haem c dissimilatory nitrite reductase from Ralstonia pickettii
Cong Han, Gareth S. A. Wright, Karl Fisher, Stephen E. J. Rigby, Robert R. Eady and S. Samar Hasnain..........219‑226
Published as BJ Immediate Publication 13 March 2012, doi:10.1042/BJ20111623
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Characterization of the evolutionarily conserved iron–sulfur cluster of sirohydrochlorin ferrochelatase from Arabidopsis thaliana
Kaushik Saha, Michael E. Webb, Stephen E. J. Rigby, Helen K. Leech, Martin J. Warren and Alison G. Smith..........227‑237
Published as BJ Immediate Publication 13 March 2012, doi:10.1042/BJ20111993
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Cyanide is an adequate agonist of the plant hormone ethylene for studying signalling of sensor kinase ETR1 at the molecular level
Melanie M. A. Bisson and Georg Groth..........261‑267
Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20111447
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group
Cecilia Bartolucci, Jure Stojan, Qian‑sheng Yu, Nigel H. Greig and Doriano Lamba..........269‑277
Published as BJ Immediate Publication 6 March 2012, doi:10.1042/BJ20111675
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells
Zhiwei Zhao, Jingjing Wang, Jingsheng Tang, Xinyu Liu, Qian Zhong, Fang Wang, Wenbin Hu, Zhu Yuan, Chunlai Nie and Yuquan Wei..........291‑301
Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20111855
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28–MDM2–p53 complexes and by preventing the ubiquitination and degradation of p53
Nian‑Kang Sun, Shang‑Lang Huang, Kun‑Yi Chien and Chuck C.‑K. Chao..........303‑314
Published as BJ Immediate Publication 8 March 2012, doi:10.1042/BJ20112223
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells
Shu‑Ching Mary Wang, Dennis H. Dowhan, Natalie A. Eriksson and George E. O. Muscat..........323‑331
Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112033
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely availableFeedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target
Alejandro Giraldo, Oliver P. T. Barrett, Marcus J. Tindall, Stephen J. Fuller, Emre Amirak, Bonhi S. Bhattacharya, Peter H. Sugden and Angela Clerk..........343‑355
Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20120125
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production
Sun Ah Ham, Jung Seok Hwang, Taesik Yoo, Hanna Lee, Eun Sil Kang, Chankyu Park, Jae‑Wook Oh, Hoon Taek Lee, Gyesik Min, Jin‑Hoi Kim and Han Geuk Seo..........27‑38
Published as BJ Immediate Publication 16 February 2012, doi:10.1042/BJ20111832
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The role of the Snf1 kinase in the adaptive response of Saccharomyces cerevisiae to alkaline pH stress
Antonio Casamayor, Raquel Serrano, María Platara, Carlos Casado, Amparo Ruiz and Joaquín Ariño..........39‑49
Published as BJ Immediate Publication 28 February 2012, doi:10.1042/BJ20112099
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Copper redistribution in murine macrophages in response to Salmonella infection
Maud E. S. Achard, Sian L. Stafford, Nilesh J. Bokil, Jy Chartres, Paul V. Bernhardt, Mark A. Schembri, Matthew J. Sweet and Alastair G. McEwan..........51‑57
Published as BJ Immediate Publication 28 February 2012, doi:10.1042/BJ20112180
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
The Bcl-2 proteins Noxa and Bcl-xL co-ordinately regulate oxidative stress-induced apoptosis
Colins O. Eno, Guoping Zhao, Kristen E. Olberding and Chi Li..........69‑78
Published as BJ Immediate Publication 1 March 2012, doi:10.1042/BJ20112023
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1
Mark E. Schnute, Matthew D. McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, John W. Rains, Troii Hall, Jill Chrencik, Michelle Kraus, Ciaran N. Cronin, Matthew Saabye, Maureen K. Highkin, Richard Broadus, Shinji Ogawa, Kristin Cukyne, Laura E. Zawadzke, Vincent Peterkin, Kaliapan Iyanar, Jeffrey A. Scholten, Jay Wendling, Hideji Fujiwara, Olga Nemirovskiy, Arthur J. Wittwer and Marek M. Nagiec..........79‑88
Published as BJ Immediate Publication 8 March 2012, doi:10.1042/BJ20111929
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
The author has paid for access to this article to be freely available Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin
Keefe T. Chan, David W. Roadcap, Nicholas Holoweckyj and James E. Bear..........89‑96
Published as BJ Immediate Publication 27 February 2012, doi:10.1042/BJ20120209
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The oligomer plasticity of the small heat-shock protein Lo18 from Oenococcus oeni influences its role in both membrane stabilization and protein protection
Magali Maitre, Stéphanie Weidmann, Aurélie Rieu, Daphna Fenel, Guy Schoehn, Christine Ebel, Jacques Coves and Jean Guzzo..........97‑104
Published as BJ Immediate Publication 24 February 2012, doi:10.1042/BJ20120066
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk
Yuri Kogan, Karin E. Halevi‑Tobias, Gili Hochman, Anna K. Baczmanska, Luc Leyns and Zvia Agur..........115‑125
Published as BJ Immediate Publication 22 February 2012, doi:10.1042/BJ20111887
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis
Yilin Huo, Valentina Iadevaia, Zhong Yao, Isabelle Kelly, Sabina Cosulich, Sylvie Guichard, Leonard J. Foster and Christopher G. Proud..........141‑151
Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112107
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 443

Mutual co-regulation between GPI-N-acetylglucosaminyltransferase and ergosterol biosynthesis in Candida albicans
Guiliana Soraya Victoria, Bhawna Yadav, Lalremruata Hauhnar, Priyanka Jain, Shilpi Bhatnagar and Sneha Sudha Komath..........619‑625
Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20120143
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
An activity-based probe reveals dynamic protein–protein interactions mediating IGF-1R transactivation by the GABAB receptor
Xin Lin, Xin Li, Ming Jiang, Linhai Chen, Chanjuan Xu, Wenhua Zhang, Han Zhao, Bing Sun, Xiaoli Xu, Fajun Nan and Jianfeng Liu..........627‑634
Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20120188
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel
Stephen C. Harmer, Jagdeep S. Mohal, Duncan Kemp and Andrew Tinker..........635‑642
Published as BJ Immediate Publication 6 February 2012, doi:10.1042/BJ20111912
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Identification of the topology and functional domains of PAQR10
Ting Jin, Daqian Xu, Qiurong Ding, Yixuan Zhang, Chenqian Mao, Yi Pan, Zhenzhen Wang and Yan Chen..........643‑653
Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20112105
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1
Iain Scott, Bradley R. Webster, Jian H. Li and Michael N. Sack..........655‑661
Published as BJ Immediate Publication 6 February 2012, doi:10.1042/BJ20120118
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Role of individual phosphorylation sites for the 14-3-3-protein-dependent activation of yeast neutral trehalase Nth1
Dana Veisova, Eva Macakova, Lenka Rezabkova, Miroslav Sulc, Petr Vacha, Hana Sychrova, Tomas Obsil and Veronika Obsilova..........663‑670
Published as BJ Immediate Publication 9 February 2012, doi:10.1042/BJ20111615
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains
Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka and Kouhei Tsumoto..........671‑680
Published as BJ Immediate Publication 9 February 2012, doi:10.1042/BJ20112049
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition
Minkyung Kang, Suyong Choi, Soo‑Jin Jeong, Sin‑Ae Lee, Tae Kyoung Kwak, Hyeonjung Kim, Oisun Jung, Mi‑Sook Lee, Youra Ko, Jihye Ryu, Yoon‑Ju Choi, Doyoung Jeong, Hyo Jeong Lee, Sang‑Kyu Ye, Sung‑Hoon Kim and Jung Weon Lee..........691‑700
Published as BJ Immediate Publication 31 January 2012, doi:10.1042/BJ20111584
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
Ke Gong, Jia Xie, Hong Yi and Wenhua Li..........735‑746
Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20111685
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells
Hai Li and Jingwen Liu..........757‑768
Published as BJ Immediate Publication 31 January 2012, doi:10.1042/BJ20111645
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Transthyretin is a metallopeptidase with an inducible active site
Márcia A. Liz, Sérgio C. Leite, Luiz Juliano, Maria J. Saraiva, Ana M. Damas, Daniel Bur and Mónica M. Sousa..........769‑778
Published as BJ Immediate Publication 15 February 2012, doi:10.1042/BJ20111690
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The mouse Mageb18 gene encodes a ubiquitously expressed type I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells
Yuquan Lin, Ti Wen, Xianyi Meng, Zhenzhou Wu, Liqing Zhao, Puyue Wang, Zhangyong Hong and Zhinan Yin..........779‑788
Published as BJ Immediate Publication 15 February 2012, doi:10.1042/BJ20112054
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
p53 Ser15 phosphorylation disrupts the p53–RPA70 complex and induces RPA70-mediated DNA repair in hypoxia
Esha Madan, Rajan Gogna and Uttam Pati..........811‑820
Published as BJ Immediate Publication 30 January 2012, doi:10.1042/BJ20111627
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation
Xiaoling Wang, Ji Wang, Vera Huang, Robert F. Place and Long‑Cheng Li..........821‑828
Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20111491
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The ligand specificity of the G-protein-coupled receptor GPR34
Lars Ritscher, Eva Engemaier, Claudia Stäubert, Ines Liebscher, Philipp Schmidt, Thomas Hermsdorf, Holger Römpler, Angela Schulz and Torsten Schöneberg..........841‑850
Published as BJ Immediate Publication 20 February 2012, doi:10.1042/BJ20112090
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter
Maria A. Whitehead, Michele Bombardieri, Costantino Pitzalis and Bart Vanhaesebroeck..........857‑867
Published as BJ Immediate Publication 29 February 2012, doi:10.1042/BJ20112214
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available A novel lectin from Agrocybe aegerita shows high binding selectivity for terminal N-acetylglucosamine
Shuai Jiang, Yijie Chen, Man Wang, Yalin Yin, Yongfu Pan, Bianli Gu, Guojun Yu, Yamu Li, Barry Hon Cheung Wong, Yi Liang and Hui Sun..........369‑378
Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20112061
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells
Claudia Brunelli, Carla Amici, Mara Angelini, Chiara Fracassi, Giuseppe Belardo and M. Gabriella Santoro..........379‑386
Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20111236
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The Golgi-associated long coiled-coil protein NECC1 participates in the control of the regulated secretory pathway in PC12 cells
David Cruz‑García, Alberto Díaz‑Ruiz, Yoana Rabanal‑Ruiz, Juan R. Peinado, Francisco Gracia‑Navarro, Justo P. Castaño, Maité Montero‑Hadjadje, Marie‑Christine Tonon, Hubert Vaudry, Youssef Anouar, Rafael Vázquez‑Martínez and María M. Malagón..........387‑396
Published as BJ Immediate Publication 18 January 2012, doi:10.1042/BJ20110554
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding
Robert H. Jenkins, John Martin, Aled O. Phillips, Timothy Bowen and Donald J. Fraser..........407‑416
Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20111861
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase
Watchalee Chuenchor, Tzanko I. Doukov, Melissa Resto, Andrew Chang and Barbara Gerratana..........417‑426
Published as BJ Immediate Publication 26 January 2012, doi:10.1042/BJ20112210
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana
Heike Riegler, Thomas Herter, Irina Grishkovskaya, Anja Lude, Malgorzata Ryngajllo, Marie E. Bolger, Bernd Essigmann and Björn Usadel..........427‑437
Published as BJ Immediate Publication 13 February 2012, doi:10.1042/BJ20112071
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways
Anja Hafner, Nataša Obermajer and Janko Kos..........439‑450
Published as BJ Immediate Publication 19 January 2012, doi:10.1042/BJ20111351
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1
Dakshnamurthy Selvakumar, Marian J. Drescher, Jayme R. Dowdall, Khalid M. Khan, James S. Hatfield, Neeliyath A. Ramakrishnan and Dennis G. Drescher..........463‑476
Published as BJ Immediate Publication 17 January 2012, doi:10.1042/BJ20111255
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity
Min Tan, Wei Yan, Ru‑Juan Liu, Meng Wang, Xin Chen, Xiao‑Long Zhou and En‑Duo Wang..........477‑484
Published as BJ Immediate Publication 1 February 2012, doi:10.1042/BJ20111925
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available 3′-5′ Phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo
Elie Toledano, Vasily Ogryzko, Antoine Danchin, Daniel Ladant and Undine Mechold..........485‑490
Published as BJ Immediate Publication 12 January 2012, doi:10.1042/BJ20111057
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration
Alexander Kapustin, Victoria Stepanova, Natalia Aniol, Douglas B. Cines, Alexei Poliakov, Serge Yarovoi, Tatiana Lebedeva, Robin Wait, Grigory Ryzhakov, Yelena Parfyonova, Yaroslav Gursky, Hiromi Yanagisawa, Mikhail Minashkin, Robert Beabealashvilli, Alexander Vorotnikov, Alex Bobik and Vsevolod Tkachuk..........491‑503
Published as BJ Immediate Publication 26 January 2012, doi:10.1042/BJ20110348
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Oxygen activation in neuronal NO synthase: resolving the consecutive mono-oxygenation steps
Davide Papale, Chiara Bruckmann, Ben Gazur, Caroline S. Miles, Christopher G. Mowat and Simon Daff..........505‑514
Published as BJ Immediate Publication 3 February 2012, doi:10.1042/BJ20111644
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Calcium/calmodulin inhibition of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase provides a possible link between calcium and brassinosteroid signalling
Man‑Ho Oh, Hyoung Seok Kim, Xia Wu, Steven D. Clouse, Raymond E. Zielinski and Steven C. Huber..........515‑523
Published as BJ Immediate Publication 7 February 2012, doi:10.1042/BJ20111871
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Novel structural arrangement of nematode cystathionine β-synthases: characterization of Caenorhabditis elegans CBS-1
Roman Vozdek, Aleš Hnízda, Jakub Krijt, Marta Kostrouchová and Viktor Kožich..........535‑547
Published as BJ Immediate Publication 13 January 2012, doi:10.1042/BJ20111478
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay
Judith Elkaim, Michel Castroviejo, Driss Bennani, Said Taouji, Nathalie Allain, Michel Laguerre, Jean Rosenbaum, Jean Dessolin and Patrick Lestienne..........549‑559
Published as BJ Immediate Publication 24 January 2012, doi:10.1042/BJ20111779
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Regulation of human microsomal prostaglandin E synthase-1 by IL-1β requires a distal enhancer element with a unique role for C/EBPβ
Jewell N. Walters, Justin S. Bickford, Kimberly J. Newsom, Dawn E. Beachy, Sarah J. Barilovits, John‑David Herlihy and Harry S. Nick..........561‑571
Published as BJ Immediate Publication 20 January 2012, doi:10.1042/BJ20111801
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA
Shinya Matsumoto, Takeshi Uchiumi, Hiroyuki Tanamachi, Toshiro Saito, Mikako Yagi, Shinya Takazaki, Tomotake Kanki and Dongchon Kang..........573‑584
Published as BJ Immediate Publication 27 January 2012, doi:10.1042/BJ20111728
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
n−3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation
Tim Y. Hou, Jennifer M. Monk, Yang‑Yi Fan, Rola Barhoumi, Yong Q. Chen, Gonzalo M. Rivera, David N. McMurray and Robert S. Chapkin..........27‑37
Published as BJ Immediate Publication 18 January 2012, doi:10.1042/BJ20111589
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Structure–function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana
Hoyeun Kim, Sang Hyeon Na, So‑Young Lee, Young‑Min Jeong, Hyun‑Ju Hwang, Jae Young Hur, Sang‑Hyun Park, Je‑Chang Woo and Sang‑Gu Kim..........49‑56
Published as BJ Immediate Publication 3 January 2012, doi:10.1042/BJ20111308
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death
Ayano Fukuhara, Mao Yamada, Ko Fujimori, Yuya Miyamoto, Toshihide Kusumoto, Hidemitsu Nakajima and Takashi Inui..........75‑84
Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20111889
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Biochemical identification of the OsMKK6–OsMPK3 signalling pathway for chilling stress tolerance in rice1
Guosheng Xie, Hideki Kato and Ryozo Imai..........95‑102
Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20111792
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Serum copper as a novel biomarker for resistance to thyroid hormone
Jens Mittag, Thomas Behrends, Kristina Nordström, Joao Anselmo, Björn Vennström and Lutz Schomburg..........103‑109
Published as BJ Immediate Publication 6 January 2012, doi:10.1042/BJ20111817
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist
Kristy J. Wilson, Christopher P. Mill, Richard M. Gallo, Elizabeth M. Cameron, Henry VanBrocklin, Jeffrey Settleman and David J. Riese..........133‑144
Published as BJ Immediate Publication 5 January 2012, doi:10.1042/BJ20110921
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
ROCKII Ser1366 phosphorylation reflects the activation status
Hsiang‑Hao Chuang, Chih‑Hsuan Yang, Yeou‑Guang Tsay, Chih‑Yi Hsu, Ling‑Ming Tseng, Zee‑Fen Chang and Hsiao‑Hui Lee..........145‑151
Published as BJ Immediate Publication 24 January 2012, doi:10.1042/BJ20111839
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α
Mark A. Barber, Annick Hendrickx, Monique Beullens, Hugo Ceulemans, David Oxley, Sylvia Thelen, Marcus Thelen, Mathieu Bollen and Heidi C. E. Welch..........173‑183
Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20112078
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase
Laurent Bultot, Bruno Guigas, Alexander Von Wilamowitz‑Moellendorff, Liliane Maisin, Didier Vertommen, Nusrat Hussain, Monique Beullens, Joan J. Guinovart, Marc Foretz, Benoît Viollet, Kei Sakamoto, Louis Hue and Mark H. Rider..........193‑203
Published as BJ Immediate Publication 11 January 2012, doi:10.1042/BJ20112026
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
Mingzhan Xue, Naila Rabbani, Hiroshi Momiji, Precious Imbasi, M. Maqsud Anwar, Neil Kitteringham, B. Kevin Park, Tomokazu Souma, Takashi Moriguchi, Masayuki Yamamoto and Paul J. Thornalley..........213‑222
Published as BJ Immediate Publication 22 December 2011, doi:10.1042/BJ20111648
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries
Nunzianna Doti, Pasqualina L. Scognamiglio, Stefania Madonna, Claudia Scarponi, Menotti Ruvo, Giuseppe Perretta, Cristina Albanesi and Daniela Marasco..........231‑240
Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111647
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms
Craigen R. Nes, Ujjal K. Singha, Jialin Liu, Kulothungan Ganapathy, Fernando Villalta, Michael R. Waterman, Galina I. Lepesheva, Minu Chaudhuri and W. David Nes..........267‑277
Published as BJ Immediate Publication 19 December 2011, doi:10.1042/BJ20111849
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase
Katrin Watschinger, Julian E. Fuchs, Vladimir Yarov‑Yarovoy, Markus A. Keller, Georg Golderer, Albin Hermetter, Gabriele Werner‑Felmayer, Nicolas Hulo and Ernst R. Werner..........279‑286
Published as BJ Immediate Publication 6 January 2012, doi:10.1042/BJ20111509
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier
Luis A. Luévano‑Martínez, Carlos Barba‑Ostria, Daniela Araiza‑Olivera, Natalia Chiquete‑Félix, Sergio Guerrero‑Castillo, Eduardo Rial, Dimitris Georgellis and Salvador Uribe‑Carvajal..........317‑325
Published as BJ Immediate Publication 11 January 2012, doi:10.1042/BJ20110992
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 442

PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances
Lomon So and David A. Fruman..........465‑481
Published on the Internet 24 February 2012, doi:10.1042/BJ20112092
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Animation
Allosteric antibody inhibition of human hepsin protease
Tobias Koschubs, Stefan Dengl, Harald Dürr, Klaus Kaluza, Guy Georges, Christiane Hartl, Stefan Jennewein, Martin Lanzendörfer, Johannes Auer, Alvin Stern, Kuo‑Sen Huang, Kathryn Packman, Ueli Gubler, Dirk Kostrewa, Stefan Ries, Silke Hansen, Ulrich Kohnert, Patrick Cramer and Olaf Mundigl..........483‑494
Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111317
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The chromatin-binding protein HMGN3 stimulates histone acetylation and transcription across the Glyt1 gene
Gráinne Barkess, Yuri Postnikov, Chrisanne D. Campos, Shivam Mishra, Gokula Mohan, Sakshi Verma, Michael Bustin and Katherine L. West..........495‑505
Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111502
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity
Sohini Chakrabortee, Yun Liu, Liao Zhang, Helena R. Matthews, Hanrui Zhang, Ni Pan, Chun‑ru Cheng, Shu‑hong Guan, De‑an Guo, Zebo Huang, Yizhi Zheng and Alan Tunnacliffe..........507‑515
Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111661
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structural determinants for rCNT2 sorting to the plasma membrane of polarized and non-polarized cells
Itziar Pinilla‑Macua, F. Javier Casado and Marçal Pastor‑Anglada..........517‑525
Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20110605
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
Yu Qiu, Wen Zhang, Chen Zhao, Yan Wang, Weiwei Wang, Jiahai Zhang, Zhiyong Zhang, Guohong Li, Yunyu Shi, Xiaoming Tu and Jihui Wu..........527‑538
Published as BJ Immediate Publication 13 December 2011, doi:10.1042/BJ20111885
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
Ersin Akinci, Anannya Banga, Lucas V. Greder, James R. Dutton and Jonathan M. W. Slack..........539‑550
Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111678
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A Golgi-localized MATE transporter mediates iron homoeostasis under osmotic stress in Arabidopsis
Pil Joon Seo, Jungmin Park, Mi‑Jeong Park, Youn‑Sung Kim, Sang‑Gyu Kim, Jae‑Hoon Jung and Chung‑Mo Park..........551‑561
Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111311
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin
Tien‑Sheng Tseng, Chao‑Sheng Cheng, Dian‑Jiun Chen, Min‑Fang Shih, Yu‑Nan Liu, Shang‑Te Danny Hsu and Ping‑Chiang Lyu..........563‑572
Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111360
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
RCD1–DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana
Julia P. Vainonen, Pinja Jaspers, Michael Wrzaczek, Airi Lamminmäki, Ramesha A. Reddy, Lauri Vaahtera, Mikael Brosché and Jaakko Kangasjärvi..........573‑581
Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111739
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Human-protein-derived peptides for intracellular delivery of biomolecules
Alexander K. Haas, Daniela Maisel, Juliane Adelmann, Christoffer von Schwerin, Ines Kahnt and Ulrich Brinkmann..........583‑593
Published as BJ Immediate Publication 13 December 2011, doi:10.1042/BJ20111973
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)
Stephen J. Fuller, Liam J. McGuffin, Andrew K. Marshall, Alejandro Giraldo, Sampsa Pikkarainen, Angela Clerk and Peter H. Sugden..........595‑610
Published as BJ Immediate Publication 9 January 2012, doi:10.1042/BJ20112000
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1
Rhiannon J. Whiting, Christine J. Payne, Jiulia Satiaputra, Nicole Kucera, Theresa W. Qiu, Sevgi Irtegun, Natalie J. Gunn, Neli S. Lavova‑Azmanova, Terrence D. Mulhern and Evan Ingley..........611‑620
Published as BJ Immediate Publication 24 February 2012, doi:10.1042/BJ20111485
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Plastoquinone-9 biosynthesis in cyanobacteria differs from that in plants and involves a novel 4-hydroxybenzoate solanesyltransferase
Radin Sadre, Christian Pfaff and Stephan Buchkremer..........621‑629
Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111796
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response
Craig McKibbin, Alina Mares, Michela Piacenti, Helen Williams, Peristera Roboti, Marjo Puumalainen, Anna C. Callan, Karolina Lesiak‑Mieczkowska, Stig Linder, Hanna Harant, Stephen High, Sabine L. Flitsch, Roger C. Whitehead and Eileithyia Swanton..........639‑648
Published as BJ Immediate Publication 6 December 2011, doi:10.1042/BJ20111220
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
Maria N. Navarro, Linda V. Sinclair, Carmen Feijoo‑Carnero, Rosemary Clarke, Sharon A. Matthews and Doreen A. Cantrell..........649‑659
Published as BJ Immediate Publication 10 January 2012, doi:10.1042/BJ20111700
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A cohesin–RAD21 interactome
Anil K. Panigrahi, Nenggang Zhang, Subhendu K. Otta and Debananda Pati..........661‑670
Published as BJ Immediate Publication 7 December 2011, doi:10.1042/BJ20111745
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A novel glutaredoxin domain-containing peroxiredoxin ‘All1541’ protects the N2-fixing cyanobacterium Anabaena PCC 7120 from oxidative stress
Manisha Banerjee, Anand Ballal and Shree K. Apte..........671‑680
Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111877
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M. Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H. Rider, Didier Vertommen and Christopher G. Proud..........681‑692
Published as BJ Immediate Publication 4 January 2012, doi:10.1042/BJ20111530
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes
Yu Wu, Nora Steinbergs, Tracy Murray‑Stewart, Laurence J. Marton and Robert A. Casero..........693‑701
Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111271
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Folded functional lipid-poor apolipoprotein A-I obtained by heating of high-density lipoproteins: relevance to high-density lipoprotein biogenesis
Shobini Jayaraman, Giorgio Cavigiolio and Olga Gursky..........703‑712
Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111831
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Selective reduction of hydroperoxyeicosatetraenoic acids to their hydroxy derivatives by apolipoprotein D: implications for lipid antioxidant activity and Alzheimer's disease
Surabhi Bhatia, Bianca Knoch, Jenny Wong, Woojin S. Kim, Paul L. Else, Aaron J. Oakley and Brett Garner..........713‑721
Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111166
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade
Graeme I. Lancaster, Beata Skiba, Christine Yang, Hayley T. Nicholls, Katherine G. Langley, M. H. Stanley Chan, Clinton R. Bruce, Gordon W. Rewcastle, Peter R. Shepherd, Michael Karin and Mark A. Febbraio..........723‑732
Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20112037
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation
Paul John Andralojc, Pippa J. Madgwick, Yong Tao, Alfred Keys, Jane L. Ward, Michael H. Beale, Jane E. Loveland, Phil J. Jackson, Antony C. Willis, Steven Gutteridge and Martin A.J. Parry..........733‑742
Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111443
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence
Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu Chen and Jeak Ling Ding..........263‑271
Published on the Internet 13 February 2012, doi:10.1042/BJ20111653
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influences enzymatic activity
Quan Yu and Xiaofeng Zheng..........283‑291
Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111598
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways
Ming‑Cheng Chang, Chi‑An Chen, Pao‑Jen Chen, Ying‑Cheng Chiang, Yu‑Li Chen, Tsui‑Lien Mao, Han‑Wei Lin, Wen‑Hsien Lin Chiang and Wen‑Fang Cheng..........293‑302
Published as BJ Immediate Publication 14 October 2011, doi:10.1042/BJ20110282
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma
Hesan Luo, Jinjin Zou, Zhongyi Dong, Qin Zeng, Dehua Wu and Li Liu..........311‑321
Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111517
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling
Gonzalo Pérez‑Siles, Enrique Núñez, Antonio Morreale, Esperanza Jiménez, Alejandra Leo‑Macías, Guillermo Pita, Francesca Cherubino, Rachele Sangaletti, Elena Bossi, Ángel R. Ortíz, Carmen Aragón and Beatriz López‑Corcuera..........323‑334
Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20110247
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Lactococcus lactis HemW (HemN) is a haem-binding protein with a putative role in haem trafficking
Helge K. Abicht, Jacobo Martinez, Gunhild Layer, Dieter Jahn and Marc Solioz..........335‑343
Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111618
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Functional mapping of the disparate activities of the yeast moonlighting protein Hal3
J. Albert Abrie, Asier González, Erick Strauss and Joaquín Ariño..........357‑368
Published as BJ Immediate Publication 29 November 2011, doi:10.1042/BJ20111466
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation
Benjamin Selles, Martin Hugo, Madia Trujillo, Vaibhav Srivastava, Gunnar Wingsle, Jean‑Pierre Jacquot, Rafael Radi and Nicolas Rouhier..........369‑380
Published as BJ Immediate Publication 29 November 2011, doi:10.1042/BJ20111378
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors
Elisa Merklinger, Yana Gofman, Alexej Kedrov, Arnold J. M. Driessen, Nir Ben‑Tal, Yechiel Shai and Doron Rapaport..........381‑389
Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111363
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage
Suchismita Chandran and Carolyn E. Machamer..........391‑401
Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111461
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins
Yi‑Ling Chen, Kai‑Fa Huang, Wen‑Chih Kuo, Yan‑Chung Lo, Yu‑May Lee and Andrew H.‑J. Wang..........403‑412
Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20110535
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins
Nobuyuki Tachi, Yuichi Hashimoto and Masaaki Matsuoka..........413‑422
Published as BJ Immediate Publication 24 November 2011, doi:10.1042/BJ20100993
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Oxidation of Met1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure
Vincenzo De Filippis, Stefano Lancellotti, Fabio Maset, Barbara Spolaore, Nicola Pozzi, Giovanni Gambaro, Laura Oggianu, Lorenzo A. Calò and Raimondo De Cristofaro..........423‑432
Published as BJ Immediate Publication 18 November 2011, doi:10.1042/BJ20111798
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions
Paramita Ray, Sarah A. Lewin, Laura Anne Mihalko, Sasha‑Cai Lesher‑Perez, Shuichi Takayama, Kathryn E. Luker and Gary D. Luker..........433‑442
Published as BJ Immediate Publication 6 December 2011, doi:10.1042/BJ20111341
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition
Jose M. Martin‑Garcia, Javier Ruiz‑Sanz and Irene Luque..........443‑451
Published as BJ Immediate Publication 24 November 2011, doi:10.1042/BJ20111089
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
New insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratory
Aleksander W. Roszak, Vladimíra Moulisová, Adhie D. P. Reksodipuro, Alastair T. Gardiner, Ritsuko Fujii, Hideki Hashimoto, Neil W. Isaacs and Richard J. Cogdell..........27‑37
Published as BJ Immediate Publication 4 November 2011, doi:10.1042/BJ20111540
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Palmitoylation and trafficking of GAD65 are impaired in a cellular model of Huntington's disease
Daniel B. Rush, Rebecca T. Leon, Mark H. McCollum, Ryan W. Treu and Jianning Wei..........39‑48
Published as BJ Immediate Publication 21 November 2011, doi:10.1042/BJ20110679
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP
Sagar Darvekar, Sylvia Sagen Johnsen, Agnete Bratsberg Eriksen, Terje Johansen and Eva Sjøttem..........65‑75
Published as BJ Immediate Publication 14 November 2011, doi:10.1042/BJ20111230
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Staphylococcus aureus DinG, a helicase that has evolved into a nuclease
Anne‑Marie McRobbie, Bjoern Meyer, Christophe Rouillon, Biljana Petrovic‑Stojanovska, Huanting Liu and Malcolm F. White..........77‑84
Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111903
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
EscI: a crucial component of the type III secretion system forms the inner rod structure in enteropathogenic Escherichia coli
Neta Sal‑Man, Wanyin Deng and B. Brett Finlay..........119‑125
Published as BJ Immediate Publication 17 November 2011, doi:10.1042/BJ20111620
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Induction of group IVC phospholipase A2 in allergic asthma: transcriptional regulation by TNFα in bronchoepithelial cells
Justin S. Bickford, Kimberly J. Newsom, John‑David Herlihy, Christian Mueller, Benjamin Keeler, Xiaolei Qiu, Jewell N. Walters, Nan Su, Shannon M. Wallet, Terence R. Flotte and Harry S. Nick..........127‑137
Published as BJ Immediate Publication 15 November 2011, doi:10.1042/BJ20111269
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
CaMKII-γ mediates phosphorylation of BAD at Ser170 to regulate cytokine-dependent survival and proliferation
Payman Hojabrpour, Ivan Waissbluth, Mazyar Ghaffari, Michael E. Cox and Vincent Duronio..........139‑149
Published as BJ Immediate Publication 22 November 2011, doi:10.1042/BJ20111256
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo
Greg C. Smith, Wee Kiat Ong, Gordon W. Rewcastle, Jackie D. Kendall, Weiping Han and Peter R. Shepherd..........161‑169
Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111913
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Identification of 4-hydroxy-2-nonenal–histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-1
Miyuki Kumano‑Kuramochi, Yuuki Shimozu, Chika Wakita, Mayumi Ohnishi‑Kameyama, Takahiro Shibata, Shigeru Matsunaga, Yuko Takano‑Ishikawa, Jun Watanabe, Masao Goto, Qiuhong Xie, Shiro Komba, Koji Uchida and Sachiko Machida..........171‑180
Published as BJ Immediate Publication 11 November 2011, doi:10.1042/BJ20111029
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster
Chonticha Saisawang, Jantana Wongsantichon and Albert J. Ketterman..........181‑190
Published as BJ Immediate Publication 15 November 2011, doi:10.1042/BJ20111747
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells
Sofia Origanti, Shannon L. Nowotarski, Theresa D. Carr, Suzanne Sass‑Kuhn, Lan Xiao, Jian‑Ying Wang and Lisa M. Shantz..........199‑207
Published as BJ Immediate Publication 10 November 2011, doi:10.1042/BJ20111464
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35
Michael E. Harbour, Sophia Y. Breusegem and Matthew N. J. Seaman..........209‑220
Published as BJ Immediate Publication 9 November 2011, doi:10.1042/BJ20111761
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine
Puppala Muthenna, Chandrasekhar Akileshwari and G. Bhanuprakash Reddy..........221‑230
Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20110846
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data

Volume 441

The author has paid for access to this article to be freely available The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities
Matthew Brook, Lora McCracken, James P. Reddington, Zhi‑Liang Lu, Nicholas A. Morrice and Nicola K. Gray..........803‑812
Published as BJ Immediate Publication 18 October 2011, doi:10.1042/BJ20111474
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS-like domain of the molybdenum cofactor sulfurase ABA3 by cysteine-scanning mutagenesis
Markus Lehrke, Steffen Rump, Torsten Heidenreich, Josef Wissing, Ralf R. Mendel and Florian Bittner..........823‑832
Published as BJ Immediate Publication 17 October 2011, doi:10.1042/BJ20111170
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization
Lamya El Mortaji, Carlos Contreras‑Martel, Monica Moschioni, Ilaria Ferlenghi, Clothilde Manzano, Thierry Vernet, Andrea Dessen and Anne Marie Di Guilmi..........833‑841
Published as BJ Immediate Publication 21 October 2011, doi:10.1042/BJ20111397
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
α-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype
María T. Marcos‑Almaraz, José A. Rodríguez‑Gómez, José López‑Barneo and Alberto Pascual..........843‑850
Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20111640
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Large T-antigen up-regulates Kv4.3 K+ channels through Sp1, and Kv4.3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II
Qi Li, Ying Zhang, Yue Sheng, Rong Huo, Bo Sun, Xue Teng, Na Li, Jiu‑Xin Zhu, Bao‑Feng Yang and De‑Li Dong..........859‑867
Published as BJ Immediate Publication 25 October 2011, doi:10.1042/BJ20111604
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Detection of Rho GEF and GAP activity through a sensitive split luciferase assay system
Erik L. Anderson and Michael J. Hamann..........869‑879
Published as BJ Immediate Publication 17 October 2011, doi:10.1042/BJ20111111
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Abi-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion
Masahiro Maruoka, Mizuho Sato, Yunfeng Yuan, Masayoshi Ichiba, Ryosuke Fujii, Takuya Ogawa, Norihiro Ishida‑Kitagawa, Tatsuo Takeya and Naoki Watanabe..........889‑899
Published as BJ Immediate Publication 20 October 2011, doi:10.1042/BJ20110951
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression
Newton J. Hurst, Abdo J. Najy, Carolyn V. Ustach, Lisa Movilla and Hyeong‑Reh Choi Kim..........909‑918
Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20111020
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1
Lisa Dohrn, Daniela Salles, Simone Y. Siehler, Julia Kaufmann and Lisa Wiesmüller..........919‑926
Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20110314
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration
Ning Xiao, Hui Li, Jian Luo, Rui Wang, Haiquan Chen, Jiquan Chen and Ping Wang..........979‑986
Published as BJ Immediate Publication 27 October 2011, doi:10.1042/BJ20111358
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form
Genta Ito and Takeshi Iwatsubo..........987‑994
Published as BJ Immediate Publication 2 November 2011, doi:10.1042/BJ20111215
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling
Ajanthy Arulpragasam, Aaron L. Magno, Evan Ingley, Suzanne J. Brown, Arthur D. Conigrave, Thomas Ratajczak and Bryan K. Ward..........995‑1006
Published as BJ Immediate Publication 19 October 2011, doi:10.1042/BJ20111277
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Homo- and hetero-dimeric architecture of the human liver Na+-dependent taurocholate co-transporting protein
Ingrid T. G. W. Bijsmans, Rianne A. M. Bouwmeester, Joachim Geyer, Klaas Nico Faber and Stan F. J. van de Graaf..........1007‑1015
Published as BJ Immediate Publication 26 October 2011, doi:10.1042/BJ20111234
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking
Katarzyna Banaszak, Vlad Martin‑Diaconescu, Matteo Bellucci, Barbara Zambelli, Wojciech Rypniewski, Michael J. Maroney and Stefano Ciurli..........1017‑1026
Published as BJ Immediate Publication 20 October 2011, doi:10.1042/BJ20111659
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
Violetta Soura, Maris Stewart‑Parker, Thomas L. Williams, Arjuna Ratnayaka, Joe Atherton, Kirsti Gorringe, Jack Tuffin, Elisabeth Darwent, Roma Rambaran, William Klein, Pascale Lacor, Kevin Staras, Julian Thorpe and Louise C. Serpell..........579‑590
Published as BJ Immediate Publication 29 September 2011, doi:10.1042/BJ20110749
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition
Peilong Lu, Guifeng Lu, Chuangye Yan, Li Wang, Wenqi Li and Ping Yin..........591‑597
Published as BJ Immediate Publication 30 September 2011, doi:10.1042/BJ20111385
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite
Milos R. Filipovic, Jan Miljkovic, Andrea Allgäuer, Ricardo Chaurio, Tatyana Shubina, Martin Herrmann and Ivana Ivanovic‑Burmazovic..........609‑621
Published as BJ Immediate Publication 28 September 2011, doi:10.1042/BJ20111389
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Metallothioneins protect cytosolic creatine kinases against stress induced by nitrogen-based oxidants
Zhe Chen, Jie Li, Tong‑Jin Zhao, Xu‑Hui Li, Fan‑Guo Meng, Hang Mu, Yong‑Bin Yan and Hai‑Meng Zhou..........623‑632
Published as BJ Immediate Publication 3 October 2011, doi:10.1042/BJ20111565
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
The author has paid for access to this article to be freely available ADP-ribose polymers localized on Ctcf–Parp1–Dnmt1 complex prevent methylation of Ctcf target sites
Michele Zampieri, Tiziana Guastafierro, Roberta Calabrese, Fabio Ciccarone, Maria G. Bacalini, Anna Reale, Mariagrazia Perilli, Claudio Passananti and Paola Caiafa..........645‑652
Published as BJ Immediate Publication 11 October 2011, doi:10.1042/BJ20111417
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia
Guo‑Min Shen, Ying‑Ze Zhao, Ming‑Tai Chen, Feng‑Lin Zhang, Xiao‑Ling Liu, Yi Wang, Chang‑Zheng Liu, Jia Yu and Jun‑Wu Zhang..........675‑683
Published as BJ Immediate Publication 4 October 2011, doi:10.1042/BJ20111377
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Chondroitin 4-O-sulfotransferase-2 regulates the number of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1
Tomomi Izumikawa, Toshiyasu Koike and Hiroshi Kitagawa..........697‑705
Published as BJ Immediate Publication 27 September 2011, doi:10.1042/BJ20111472
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling
Khandaker Ahtesham Ahmed, Tomohiro Sawa, Hideshi Ihara, Shingo Kasamatsu, Jun Yoshitake, Md. Mizanur Rahaman, Tatsuya Okamoto, Shigemoto Fujii and Takaaki Akaike..........719‑730
Published as BJ Immediate Publication 4 October 2011, doi:10.1042/BJ20111130
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase
Susan Treves, Raphael Thurnheer, Barbara Mosca, Mirko Vukcevic, Leda Bergamelli, Rebecca Voltan, Vitus Oberhauser, Michel Ronjat, Laszlo Csernoch, Peter Szentesi and Francesco Zorzato..........731‑741
Published as BJ Immediate Publication 14 October 2011, doi:10.1042/BJ20111457
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Glu106 in the Orai1 pore contributes to fast Ca2+-dependent inactivation and pH dependence of Ca2+ release-activated Ca2+ (CRAC) current
Nathan R. Scrimgeour, David P. Wilson and Grigori Y. Rychkov..........743‑753
Published as BJ Immediate Publication 3 October 2011, doi:10.1042/BJ20110558
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease
Rohan D. Teasdale and Brett M. Collins..........39‑59
Published on the Internet 14 December 2011, doi:10.1042/BJ20111226
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation
Murat Cirit and Jason M. Haugh..........77‑85
Published as BJ Immediate Publication 26 September 2011, doi:10.1042/BJ20110833
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Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding
J. Jasper Deuring, Colin de Haar, Chantal L. Koelewijn, Ernst J. Kuipers, Maikel P. Peppelenbosch and C. Janneke van der Woude..........87‑93
Published as BJ Immediate Publication 25 August 2011, doi:10.1042/BJ20111281
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Dissecting structure–function–stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168
Camila R. Santos, Joice H. Paiva, Maurício L. Sforça, Jorge L. Neves, Rodrigo Z. Navarro, Júnio Cota, Patrícia K. Akao, Zaira B. Hoffmam, Andréia N. Meza, Juliana H. Smetana, Maria L. Nogueira, Igor Polikarpov, José Xavier‑Neto, Fábio M. Squina, Richard J. Ward, Roberto Ruller, Ana C. Zeri and Mário T. Murakami..........95‑104
Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20110869
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Determinants of the enzymatic activity and the subcellular localization of aspartate N-acetyltransferase
Gaëlle Tahay, Elsa Wiame, Donatienne Tyteca, Pierre J. Courtoy and Emile Van Schaftingen..........105‑112
Published as BJ Immediate Publication 21 September 2011, doi:10.1042/BJ20111179
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Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Xi Wang, Likun Wang, Xi'e Wang, Fei Sun and Chih‑chen Wang..........113‑118
Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20110380
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Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
Jing‑Wen Shih, Wei‑Ting Wang, Tsung‑Yuan Tsai, Chu‑Yun Kuo, Hao‑Kang Li and Yan‑Hwa Wu Lee..........119‑129
Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20110739
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The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism
Silvia Garavaglia, Santina Bruzzone, Camilla Cassani, Laura Canella, Gianna Allegrone, Laura Sturla, Elena Mannino, Enrico Millo, Antonio De Flora and Menico Rizzi..........131‑141
Published as BJ Immediate Publication 20 September 2011, doi:10.1042/BJ20111263
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Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains
Zi‑Ren Zhou, Yu‑Hang Zhang, Shuai Liu, Ai‑Xin Song and Hong‑Yu Hu..........143‑149
Published as BJ Immediate Publication 19 August 2011, doi:10.1042/BJ20110699
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Insights into subtle conformational differences in the substrate-binding loop of fungal 17β-hydroxysteroid dehydrogenase: a combined structural and kinetic approach
Alberto Cassetta, Ivet Krastanova, Katja Kristan, Mojca Brunskole Švegelj, Doriano Lamba, Tea Lanišnik Rižner and Jure Stojan..........151‑160
Published as BJ Immediate Publication 19 September 2011, doi:10.1042/BJ20110567
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A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid
Anne Pribat, Rodnay Sormani, Mathieu Rousseau‑Gueutin, Magdalena M. Julkowska, Christa Testerink, Jerôme Joubès, Michel Castroviejo, Michel Laguerre, Christian Meyer, Véronique Germain and Christophe Rothan..........161‑171
Published as BJ Immediate Publication 24 August 2011, doi:10.1042/BJ20110776
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Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2
Christian Krintel, Karla Frydenvang, Lars Olsen, Maria T. Kristensen, Oriol de Barrios, Peter Naur, Pierre Francotte, Bernard Pirotte, Michael Gajhede and Jette S. Kastrup..........173‑178
Published as BJ Immediate Publication 7 September 2011, doi:10.1042/BJ20111221
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Revealing the structural origin of the redox-Bohr effect: the first solution structure of a cytochrome from Geobacter sulfurreducens
Leonor Morgado, Vítor B. Paixão, Marianne Schiffer, P. Raj Pokkuluri, Marta Bruix and Carlos A. Salgueiro..........179‑187
Published as BJ Immediate Publication 24 August 2011, doi:10.1042/BJ20111103
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S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt
Ruomin Di, Xiangqi Wu, Zai Chang, Xia Zhao, Qiuting Feng, Shuangshuang Lu, Qing Luan, Brian A. Hemmings, Xinli Li and Zhongzhou Yang..........199‑207
Published as BJ Immediate Publication 9 September 2011, doi:10.1042/BJ20110033
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A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family
Iraia García‑Santisteban, Sonia Bañuelos and Jose A. Rodríguez..........209‑217
Published as BJ Immediate Publication 2 September 2011, doi:10.1042/BJ20111300
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Adaptive evolution of drug targets in producer and non-producer organisms
Bjarne G. Hansen, Xin E. Sun, Hans J. Genee, Christian S. Kaas, Jakob B. Nielsen, Uffe H. Mortensen, Jens C. Frisvad and Lizbeth Hedstrom..........219‑226
Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20111278
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Targeted polyubiquitylation of RASSF1C by the Mule and SCFβ-TrCP ligases in response to DNA damage
Xin Zhou, Ting‑Ting Li, Xu Feng, Esther Hsiang, Yue Xiong, Kun‑Liang Guan and Qun‑Ying Lei..........227‑236
Published as BJ Immediate Publication 12 September 2011, doi:10.1042/BJ20111500
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The author has paid for access to this article to be freely available Translation of a minigene in the 5′ leader sequence of the enterohaemorrhagic Escherichia coli LEE1 transcription unit affects expression of the neighbouring downstream gene
Md. Shahidul Islam, Robert K. Shaw, Gad Frankel, Mark J. Pallen and Stephen J. W. Busby..........247‑253
Published as BJ Immediate Publication 6 October 2011, doi:10.1042/BJ20110912
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The author has paid for access to this article to be freely available Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice
Paul J. Meakin, Alex J. Harper, D. Lee Hamilton, Jennifer Gallagher, Alison D. McNeilly, Laura A. Burgess, Lobke M. Vaanholt, Kirsten A. Bannon, Judy Latcham, Ishrut Hussain, John R. Speakman, David R. Howlett and Michael L.J. Ashford..........285‑296
Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20110512
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BAG-1 diversely affects steroid receptor activity
Regina T. Knapp, Andrea Steiner, Ulrike Schmidt, Kathrin Hafner, Florian Holsboer and Theo Rein..........297‑303
Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20111456
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The author has paid for access to this article to be freely available Domain assembly of NAADP-gated two-pore channels
Dev Churamani, Robert Hooper, Eugen Brailoiu and Sandip Patel..........317‑323
Published as BJ Immediate Publication 12 October 2011, doi:10.1042/BJ20111617
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The author has paid for access to this article to be freely available SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation
Jacob O. Thastrup, Fatema H. Rafiqi, Alberto C. Vitari, Eulalia Pozo‑Guisado, Maria Deak, Youcef Mehellou and Dario R. Alessi..........325‑337
Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20111879
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Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system
Eddy T. H. Goh, J. Simon C. Arthur, Peter C. F. Cheung, Shizuo Akira, Rachel Toth and Philip Cohen..........339‑346
Published as BJ Immediate Publication 18 October 2011, doi:10.1042/BJ20111415
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Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n−3 polyunsaturated fatty acids
Ethan J. Anderson, Kathleen Thayne, Mitchel Harris, Kristen Carraway and Saame Raza Shaikh..........359‑366
Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20110626
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PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity
Meng‑Chieh Lin, Ya‑Chuan Liu, Ming F. Tam, Yu‑Ju Lu, Ya‑Ting Hsieh and Lih‑Yuan Lin..........367‑377
Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20111257
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Thr90 phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery
Xiaofeng Wang, Xin‑an Lu, Xiaomin Song, Wei Zhuo, Lin Jia, Yushan Jiang and Yongzhang Luo..........387‑397
Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20110855
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Phospholipase D1 mediates bFGF-induced Bcl-2 expression leading to neurite outgrowth in H19-7 cells
Sung Nyo Yoon, Kang Sik Kim, Ju Hwan Cho, Weina Ma, Hye‑Jin Choi, Sung‑Joon Kwon and Joong‑Soo Han..........407‑416
Published as BJ Immediate Publication 14 September 2011, doi:10.1042/BJ20110302
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Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans
Hanrui Zhang, Ni Pan, Siqin Xiong, Shenglong Zou, Haifeng Li, Lingyun Xiao, Zhijian Cao, Alan Tunnacliffe and Zebo Huang..........417‑424
Published as BJ Immediate Publication 5 September 2011, doi:10.1042/BJ20110621
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Identification of novel small molecules that elevate Klotho expression
Gwendalyn D. King, CiDi Chen, Mickey M. Huang, Ella Zeldich, Patricia L. Brazee, Eli R. Schuman, Maxime Robin, Gregory D. Cuny, Marcie A. Glicksman and Carmela R. Abraham..........453‑461
Published as BJ Immediate Publication 22 September 2011, doi:10.1042/BJ20101909
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Directed evolution of a temperature-, peroxide- and alkaline pH-tolerant versatile peroxidase
Eva Garcia‑Ruiz, David Gonzalez‑Perez, Francisco J. Ruiz‑Dueñas, Angel T. Martínez and Miguel Alcalde..........487‑498
Published as BJ Immediate Publication 7 October 2011, doi:10.1042/BJ20111199
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Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells
Helen C. O'Donovan, Fionnuala Hickey, Derek P. Brazil, David H. Kavanagh, Noelynn Oliver, Finian Martin, Catherine Godson and John Crean..........499‑510
Published as BJ Immediate Publication 26 August 2011, doi:10.1042/BJ20110910
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Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21
Roberta Possenti, Giampiero Muccioli, Pamela Petrocchi, Cheryl Cero, Aderville Cabassi, Lucy Vulchanova, Maureen S. Riedl, Monia Manieri, Andrea Frontini, Antonio Giordano, Saverio Cinti, Paolo Govoni, Gallia Graiani, Federico Quaini, Corrado Ghè, Elena Bresciani, Ilaria Bulgarelli, Antonio Torsello, Vittorio Locatelli, Valentina Sanghez, Bjarne D. Larsen, Jorgen S. Petersen, Paola Palanza, Stefano Parmigiani, Anna Moles, Andrea Levi and Alessandro Bartolomucci..........511‑522
Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20111165
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Online data published in 2011